52. Tumors of the prostate Flashcards

1
Q
  1. prostate adenocarcinoma

definition of prostate adenocarcinoma

A

malignant proliferation of prostate gland

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2
Q
  1. prostate adenocarcinoma

epidemiology, incidence, mortality of prostate adenocarcinoma

A
mostly in men over 50 years old
# 1 incidence of male malignancy
#2 mortality of male malignancy
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3
Q
  1. prostate adenocarcinoma

tumor marker of prostate adenocarcinoma

A

elevated prostate specific antigen (PSA)

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4
Q
  1. prostate adenocarcinoma

location of adenocarcinoma

A

peripheral, posterior part of prostate

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5
Q
  1. prostate adenocarcinoma

metastasis of prostate adenocarcinoma

A

bone metastasis (lumbar spine, pelvis)

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6
Q
  1. prostate adenocarcinoma

marker, symptom of metastatic prostate adenocarcinoma

A

prostatic acid phosphatase (PAP)

low back pain

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7
Q
  1. prostate adenocarcinoma

physical diagnosis of adenocarcinoma

A

rectal digital exam

- hard, nodular, fixed prostate

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8
Q
  1. prostate adenocarcinoma

grading of adenocarcinoma

A

Gleason system (dominant pattern + next most frequent pattern)

  • grade 1 : high differentiation
  • grade 5 : no differentiation (anaplastic)
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