63. Benign and malignant bone tumors, tumor-like lesions

Question 1

63. Tumors and tumor-like lesions of the bone

types of bone forming tumor (4)

Answer 1

osteoma
osteoid osteoma
osteoblastoma
osteosarcoma

Question 2

63. Tumors and tumor-like lesions of the bone

characteristics of osteoma

• location
• related disease

Answer 2

facial bone

Gardner syndrome : autosomal dominant polyposis

Question 3

63. Tumors and tumor-like lesions of the bone

same characteristics of osteoid osteoma and osteoblastoma

Answer 3

benign tumor of osteoblast

present with bone pain

Question 4

63. Tumors and tumor-like lesions of the bone

differentiation between osteoid osteoma vs osteoblastoma

Answer 4

osteoid osteoma : located in long bone cortex, <2cm, respond to aspirin
osteoblastoma : located in vertebrae, >2cm, not respond to adpirin

Question 5

63. Tumors and tumor-like lesions of the bone

characteristics of osteosarcoma

• malignancy
• location
• risk factor (3)

Answer 5

malignant proliferation of osteoblast
metaphysis of long bone
inherited retinoblastoma, radiation exposure, paget disease

Question 6

63. Tumors and tumor-like lesions of the bone

clinical feature, characteristic morphology of osteosarcoma

Answer 6

bone pain, swelling, fracture

Codman triangle : lifting of periosteum

Question 7

63. Tumors and tumor-like lesions of the bone

types of cartilage tumor (3)

Answer 7

osteochondroma
chondroma
chondrosarcoma

Question 8

63. Tumors and tumor-like lesions of the bone

characteristics of osteochondroma

• incidence
• location
• malignancy

Answer 8

most common bone tumor (80%)
bone overlying with cartilage : lateral projection of metaphysis
can develop into chondrosarcoma

Question 9

63. Tumors and tumor-like lesions of the bone

characteristics of chondroma

• malignancy
• location

Answer 9

benign tumor of chondrocyte

medulla of small bones (hand, feet)

Question 10

63. Tumors and tumor-like lesions of the bone

characteristics of chondrosarcoma

• malignancy
• locaton
• characteristics
• metastasis

Answer 10

malignant tumor of chondrocyte
pelvis, central skeleton
with bone pain, progressive enlarging
metastasis to lung, skeleton

Question 11

63. Tumors and tumor-like lesions of the bone

definition of Ewing sarcoma

Answer 11

malignant proliferation of undifferentiated cells from neuroectiderm

Question 12

63. Tumors and tumor-like lesions of the bone

characteristics of Ewing sarcoma

• epidemiology
• genetics
• morphology

Answer 12

male children under 15
t(11,22)
onion like appearance

Question 13

63. Tumors and tumor-like lesions of the bone

definition of giant cell tumor

Answer 13

tumor from multinucleated giant cell and stromal cell

Question 14

63. Tumors and tumor-like lesions of the bone

characteristics of giant cell tumor

• epidemiology
• location
• appearance

Answer 14

young adult
epiphysis of long bone
soap bubble appearance

Question 15

63. Tumors and tumor-like lesions of the bone

tumor regions frequently metastasis to bone

Answer 15

prostate
breast
kidney
lung