5.5

Question 1

What is the relationship between male fertility and drugs?

Answer 1

opioid like drugs can inhibit Gonadotropin release hormone, resulting in infertility. GnRH analogues that suppress gonadotropin can also result in infertility. Other drugs include alkylating drugs, antiandrogens, cimetidine, and ketoconazole, all impair androgen production.

Question 2

What is the relationship between male fertility and cryptorchidism?

Answer 2

failure of descent of testes, can result in impaired sperm production, happens during fetal development, and happens due to development problems, and is related to androgen problems.

Question 3

What is the relationship between male fertility and testicular cancer?

Answer 3

Infertile men have greater risk of testicular cancer

Question 4

What is the relationship between male fertility and varicocele?

Answer 4

Dilations of pampiniform plexus of spermatic veins, found in higher rates in infertile men, not much is proven on this matter. Left spermatic vein more prone to varicocele

Question 5

What is the relationship between male fertility and infections?

Answer 5

Viral orchitis, especially mumps, can lead to infertility due to germ cell failure. STDs can cause orchitis as well.

Question 6

What is the relationship between male fertility and radiation?

Answer 6

impairs spermatogenesis

Question 7

What is the relationship between male fertility and hyperthermia?

Answer 7

prolonged high temperature is thought to induce apoptosis in the germ cell line, and cause infertility.