4.2.2.1 Pseudomonas aeruginosa Flashcards
Most clinically isolated?
Pseudomonas aeruginosa
__ of non-fermenters in nosocomial bacteremia and _______ of nosocomial infection?
75%
5 - 15%
P. aeruginosa is the leading cause of ?
nosocomial respiratory tract infection
What are the bacteria that causes Gram negative bacillary bacteremia?
- E. coli
- K. pneumoniae
- P. aeruginosa
Clinical significance of P. aeruginosa?
Otitis media
Jacuzzi/hot tub syndrome
Gram negative bacillary bacteriemia
What is the highest temp can P. aeruginosa survive which can help in multiplying faster?
42 C
What is the description for Hot tub syndrome?
Necrotizing skin rashes
What is the pulmonary disease description for P. aeruginosa?
Pneumonia causes cystic fibrosis
What are the virulence factors for P. aeruginosa?
PRotase
Hemolysins
Lecithinase
Elastase
Dnase
(PHLED)
Exotoxins (Exotoxin A)
Alginate
Inherently resistant to antimicrobial agents
Function of Exotoxin A?
Inhibits protein synthesis
Polysacchride polymer in mucoid strains?
Alginate
What is the Pigment for P. aeruginosa?
Pyocyanin
Pyoverdine (Yellow green)
What is the hemolysis for P. pseudomonas?
Beta
What is the Odor for P. aeruginosa?
Fruity, Grape like or Corn tortilla-like
P. aeruginosa grows on what agar?
Cetrimide Agar
Cetrimide Agar is what type of Agar?
Selective and Differential
Function of Citramide agar?
Enhances the production of pigments
Citrate and Acetamide? Pos or Neg?
Positive
Arginine dihydrolase? Pos or Neg
Pos
What happens in Mueller Hinton Agar for P. aeruginosa? (Color)
Blue Green
NOTE: P. aeruginosa is the 3rd most leading cause of Nosocomial vaginalis bacteremia
