3.4.6.1 Group V Non-Cultivable Flashcards
Only Mycobacterium for Non-cultivable
M. leprae
Disease for M. leprae
Hansen’s disease (Leprosy)
2 forms of Hansen’s disease
Tuberculoid leprosy
Lepromatous leprosy
Skin lesion with loss of sensation due to peripheral damage?
Tuberculoid leprosy
Extensive and progressive skin lesion with permanent nerve damage
Lepromatous leprosy
What is the optimum temp for M. leprae for Hansen’s disease?
30 C
Effective for CMI (Cell mediated Immunue response)
Tuberculoid Leprosy
Organisms are rare which may not be detected in scrapings or biopsy specimen
Ineffective for CMI (Cell mediated Immunue response) = Low immunity
Lepromatous leprosy
Organisms are abundant
What is the definitive lab diag for M. leprae?
Injection on mice following inoculation of biopsy material
House of Leprosy is locatesd?
Tala, Caloocan
Where is skin biopsy is perform in what area of the body?
Palmar area