2.9.3.1 Shigella

Question 1

Is shigella a normal flora of GIT?

Answer 1

False

Question 2

Shigella is biochemically inert?

Answer 2

True

Question 3

Shigella is closely related to what spp?

Answer 3

E. coli

Question 4

Who is the first individual to isolate Shigella?

Answer 4

Kiyoshi Shiga 1986

Question 5

What are the 4 spps of shigella?

Answer 5

dysenteriae
flexneri
boydii
sonnei

Question 6

What are the virulence factors of shigella?

Answer 6

Mediates attachment and invasion of mucosal cells
Enterotoxin (All shigella)
Neurotoxin (dysenteriae)
Shiga toxin (dysenteriae)

Question 7

Most potent Shigella spp?

Answer 7

Shigella dysenteriae

Question 8

Virulence factor that causes ulceration of the intestinal mucosa

Answer 8

Shiga toxin

Question 9

What is the antigenic structure of Shigella?

Answer 9

K and O

Question 10

What bacteria can be seen in O antigen Group A?

Answer 10

S. dysenteriae

Question 11

What bacteria can be seen in O antigen Group B?

Answer 11

S. flexneri

Question 12

What bacteria can be seen in O antigen Group C?

Answer 12

S. boynii

Question 13

What bacteria can be seen in O antigen Group D?

Answer 13

S. sonnei

Question 14

What spp. of shigella is most commonly isolated?

Answer 14

Shigella sonnei

Shigella flexneri

Question 15

Most virulent spp of Shigella?

Answer 15

S. dysenteriae type 1

Question 16

What is the Clinical infection for Shigella?

Answer 16

Shigellosis or bacillary dysentery

Question 17

What is the first stage for Shigellosis?

Answer 17

Watery diarrhea

Question 18

What happens in dysenteric phase?

Answer 18

Blood and mucoid stool

Question 19

What is the infective dose for Shigella dysentery?

Answer 19

10-200 organisms