2.1.2 Virulence factor of Enterobacteriaceae

Question 1

What are the virulence factors of Enterobacteriaceae?

Answer 1

Adherence
Toxins: Food poisoning
Invasive enzyme (Hyaluronidase)
Antibiotic resistance

Question 2

What Enterobacteriaceae causes food poisoning

Answer 2

Yersinia
E. coli
Shigella
Salmonella

YES

Question 3

What is the antibiotic resistance of Enterobacteriaceae?

Answer 3

Extended Spectrum B-Lactamase (ESBL)

Question 4

What Enterobacteriaceae has ESBL?

Answer 4

E. coli
Klebsiella oxytoca
Klebsiella pneumoniae

(S. aureus, Pseudomonas)

Question 5

Majority of Enterobacteriaceae are normal flora in?

Answer 5

Gastrointestinal tract

Question 6

Does ESBL also inhibits Carbapenem group? If it is then give example.

Answer 6

Penicillin
Monobactam
Cephalospoin

Question 7

What is the antigenic structure of Enterobacteriaceae?

Answer 7

K antigen (Capsular)
O antigen (Somatic)
H antigen (Flageller)

Question 8

What is the function of Capsular antigen?

Answer 8

Anti-phagocytic

Heat Labile
>Types:
- Virulent (VI antigen)
- K1 antigem

Question 9

What bacteria has virulent antigen (VI antigen)?

Answer 9

Salmonella enterica
Salmonella typhi

(Generally Salmonella)

Question 10

What bacteria has K1 antigen?

Answer 10

E. coli

Question 11

What is the function of Somatic antigen?

Answer 11

Heat stable
Present in cell wall (LPS) = Gram negative bacilli

Question 12

Somatic antigen helps to differentiate what organism?

Answer 12

Shigella spp. (Serotyping)

Question 13

What is the function o H antigen?

Answer 13

Heat labile
Found on the surface of flagellla

Question 14

What are the 2 major types of Enterobacteriaceae?

Answer 14

Opportunistic pathogens
Pathogenic organisms

Question 15

What happens in opportunistic pathogens?

Answer 15

Creates infection due to imbalance in GIT tract

Question 16

What happens in pathogenic organisms

Answer 16

E. coli (Produce severe type of diarrhea)
Salmonella
Shigella

Question 17

What are the Rapid Lactose Fermenter?

Answer 17

E. coli
Enterobacter
Klebsiell

(EEK)

Question 18

What are the Late Lactose fermenter?

Answer 18

Citrobacter
Hafnia
Yersinia enterocolitica
Shigella sonnei
Serretia marcescens
Arizona

Question 19

What are the non lactose fermenter?

Answer 19

Proteus
Providencia
Plesiomonas
Edwardsiella tarda
Morganella
Salmonella
Shigella

Question 20

Antigenic structure are located in?

Answer 20

Outer membrane