2.2.2 5 Major Categoris of Diarrheal Syndromes of E. coli Flashcards
What are the 5 major categories of diarrheal syndrome of E. coli?
Enterotoxigenic E.coli (ETEC)
Enteroinvasive E. coli (EIEC)
Enteropathogenic E. coli (EPEC)
Enterohemorrhagic E. coli (EHEC)
Enteroadherent E. coli (EAEC
(TIP HA)
Enterotoxigenic E. coli is also known as?
Montezuma’s revenge / Turista
What is the disease cause by Enterotoxigenic E. coli?
Epidemic diarrhea and traveler’s diarrhea
What are the Virulence factor for Enterotoxigenic E. coli?
Adhere to intestinal mucosa
Fimbria
Heat labile and heat stable enterotoxins
What is the function of heat stable and heat labile enterotoxins?
Causes excessive intestinal secretion on the mucosal lining which lead to watery diarrhea
What are the disease for Enteroinvasive E. coli?
Dysentery (Bloody Stools)
What are the virulence factor of Enteroinvasive E. coli?
INVADES ENTEROCYTES (In GIT) causing shigella like infection
What are other characteristics of Enteroinvasive E. coli
Stains may be non motile or non lactose fermenter
What are the disease cause by Enteropathogenic E. coli?
Infantile diarrhea (Watery with mucous with no blood)
What are the virulence factor of Enteropathogenic E. coli?
Bundle forming pili (Attachment to intestinal mucosa)
Most potent strain of E. coli?
Enterohemorrhagic E. coli
Enterohemorrhagic E. coli also known as?
Verotoxic E. coli (E. coli O157:H7)
What are the virulence factor of Enterohemorrhagic E. coli?
Cytotoxin (Verotoxin I & II)
0157:H7
A Cytotoxin that is similar to Shigella toxin of S. dysenteriae
Verotoxin I
It known to cause Ulceration and damages to the intestinal mucosa leading to hemorrhagic colitis or diarrhea?
Verotoxin I
What is Biochemical that is negative to 0157:H7 strain?
Sorbitol
MUG
What are the diseases for Enterohemorrhagic E. coli?
Hemorrhagic diarrhea or colitis
Hemolytic Uremic Syndrome
Abrasion and destruction in the colon caused by shigella or Verotoxin I?
Hemorrhagic diarrhea or colitis
A disease that is characterized by low platelet count, hemolytic anemia and kidney failure
Hemolytic uremic syndrome
What test use to differentiate EHEC from other strains?
Sorbitol MacConkey agar (SMaC)
Why SMaC is used to differentiate EHEC?
EHEC strain does not ferment Sorbitol
What is the result of EHEC in SMaC?(Positive indicator)
Colorless colony
Negative indicator of SMaC of other strain except EHEC?
Pink colony
What is the disease for Enteroadherent E. coli?
Associated with diarrheal syndromes and
UTIs
What are the 2 types of Enteroadherent E. coli?
Diffusely adherent
Enteroaggregative E. coli
A type of Enteroadherent E. coli that is associated with UTI and Diarrheal disease
Diffusely adherent E. coli
A type of Enteroadherent E. coli that adhere to Hep2 in a aggregatove “Stacked-brick pattern” on the cell
Enteroaggregative E. coli
What stool is produce in Enteroaggregative E. coli?
Watyer
What is the difference of infantil and watery diarrhea?
Infantile diarrhea = w/ mucous
Watery diarrhea = w/o mucous
What strains of E. coli is similar to Shigella toxin?
EIEC
What strains of E. coli is simila to Shigella dysenteriae?
EHEC