2.2.2 5 Major Categoris of Diarrheal Syndromes of E. coli

Question 1

What are the 5 major categories of diarrheal syndrome of E. coli?

Answer 1

Enterotoxigenic E.coli (ETEC)
Enteroinvasive E. coli (EIEC)
Enteropathogenic E. coli (EPEC)
Enterohemorrhagic E. coli (EHEC)
Enteroadherent E. coli (EAEC

(TIP HA)

Question 2

Enterotoxigenic E. coli is also known as?

Answer 2

Montezuma’s revenge / Turista

Question 3

What is the disease cause by Enterotoxigenic E. coli?

Answer 3

Epidemic diarrhea and traveler’s diarrhea

Question 4

What are the Virulence factor for Enterotoxigenic E. coli?

Answer 4

Adhere to intestinal mucosa
Fimbria
Heat labile and heat stable enterotoxins

Question 5

What is the function of heat stable and heat labile enterotoxins?

Answer 5

Causes excessive intestinal secretion on the mucosal lining which lead to watery diarrhea

Question 6

What are the disease for Enteroinvasive E. coli?

Answer 6

Dysentery (Bloody Stools)

Question 7

What are the virulence factor of Enteroinvasive E. coli?

Answer 7

INVADES ENTEROCYTES (In GIT) causing shigella like infection

Question 8

What are other characteristics of Enteroinvasive E. coli

Answer 8

Stains may be non motile or non lactose fermenter

Question 9

What are the disease cause by Enteropathogenic E. coli?

Answer 9

Infantile diarrhea (Watery with mucous with no blood)

Question 10

What are the virulence factor of Enteropathogenic E. coli?

Answer 10

Bundle forming pili (Attachment to intestinal mucosa)

Question 11

Most potent strain of E. coli?

Answer 11

Enterohemorrhagic E. coli

Question 12

Enterohemorrhagic E. coli also known as?

Answer 12

Verotoxic E. coli (E. coli O157:H7)

Question 13

What are the virulence factor of Enterohemorrhagic E. coli?

Answer 13

Cytotoxin (Verotoxin I & II)
0157:H7

Question 14

A Cytotoxin that is similar to Shigella toxin of S. dysenteriae

Answer 14

Verotoxin I

Question 15

It known to cause Ulceration and damages to the intestinal mucosa leading to hemorrhagic colitis or diarrhea?

Answer 15

Verotoxin I

Question 16

What is Biochemical that is negative to 0157:H7 strain?

Answer 16

Sorbitol
MUG

Question 17

What are the diseases for Enterohemorrhagic E. coli?

Answer 17

Hemorrhagic diarrhea or colitis
Hemolytic Uremic Syndrome

Question 18

Abrasion and destruction in the colon caused by shigella or Verotoxin I?

Answer 18

Hemorrhagic diarrhea or colitis

Question 19

A disease that is characterized by low platelet count, hemolytic anemia and kidney failure

Answer 19

Hemolytic uremic syndrome

Question 20

What test use to differentiate EHEC from other strains?

Answer 20

Sorbitol MacConkey agar (SMaC)

Question 21

Why SMaC is used to differentiate EHEC?

Answer 21

EHEC strain does not ferment Sorbitol

Question 22

What is the result of EHEC in SMaC?(Positive indicator)

Answer 22

Colorless colony

Question 23

Negative indicator of SMaC of other strain except EHEC?

Answer 23

Pink colony

Question 24

What is the disease for Enteroadherent E. coli?

Answer 24

Associated with diarrheal syndromes and
UTIs

Question 25

What are the 2 types of Enteroadherent E. coli?

Answer 25

Diffusely adherent
Enteroaggregative E. coli

Question 26

A type of Enteroadherent E. coli that is associated with UTI and Diarrheal disease

Answer 26

Diffusely adherent E. coli

Question 27

A type of Enteroadherent E. coli that adhere to Hep2 in a aggregatove “Stacked-brick pattern” on the cell

Answer 27

Enteroaggregative E. coli

Question 28

What stool is produce in Enteroaggregative E. coli?

Answer 28

Watyer

Question 29

What is the difference of infantil and watery diarrhea?

Answer 29

Infantile diarrhea = w/ mucous
Watery diarrhea = w/o mucous

Question 30

What strains of E. coli is similar to Shigella toxin?

Answer 30

EIEC

Question 31

What strains of E. coli is simila to Shigella dysenteriae?

Answer 31

EHEC