4.1 Flashcards

1
Q

Liver is the sole source of

A

Albumin, other plasma proteins and bile

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2
Q

Livers is the site of conversion and excretion of

A

Bilirubin (end product of hemoglobin) (jaundice)

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3
Q

Liver produces

A

Clotting factors and store vitamins

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4
Q

Risk factors for Cholelithiasis

A

Genes (Mexican/NA)
High estrogen levels (birth control)
Diabetes
Pregnancy
High fat diet
Rapid weight loss (liver makes too much cholesterol)

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5
Q

Lifestyle risk factors for developing gall stones

A

Overweight/obese
Diet high in fat/low in fiber
Rapid weight loss in short time
Diabetes

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6
Q

Uncontrollable risk factors for developing risk factors

A

Female
NA/Mexican descent
Family history of gallstones
60 years or older

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7
Q

Medical risk factors for developing gall stones

A

Having cirrhosis or sickle cell anemia
Being pregnant
Taking meds that have estrogen content

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8
Q

Clinical manifestations for Cholelithiasis

A

Many asymptomatic
RUQ pain
Fatty food intolerance
Heartburn

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9
Q

Chronic liver injury can lead to ______ and ________, which is ______

A

Scarring and cirrhosis, which is irreversible

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10
Q

Signs/Symptoms of Hepatic Disease

A

GI symptoms
Edema/Ascites
Light or clay colored stools
Dark urine
RUQ pain

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11
Q

Skin changes in hepatic disease

A

Jaundice
Bruising
Spider angioma
Palmar erythema (thenar/hypothenar eminence)

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12
Q

Neurologic Involvement in Hepatic Disease

A

Confusion
Hyperactive reflexes
Asterixis (liver flapping)
Sleep disturbances
Muscle tremors

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13
Q

Bilirubin is a waste product when the liver breaks down

A

Old RBCs (normal value .1-1.0 mg/dL)

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14
Q

Normally, bile converted from bilirubin causes

A

Brown coloration of stool

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15
Q

Light colored stools and urine the color of tea/cola indicate

A

Inability of liver or biliary system to excrete bilirubin properly

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16
Q

Jaundice is due to

A

Hyperbilirubinemia
Defect in bilirubin metabolism
Liver disease
Obstruction of bile flow

17
Q

Causes of Ascites

A

Cirrhosis with portal hypertension
Congestive heart failure, ab malignancies, malnutrition

18
Q

Clinical manifestations of Ascites

A

Weight gain (swelling of ankles/feet)
Ab swelling and pain
Respiratory distress
Secondary bacterial infection (put in high Fowler position)

19
Q

Causes of Cirrhosis

A

Alcohol abuse
Hepatitis C
Nonalcoholic liver disease

20
Q

Risk factors for Cirrhosis

A

Excessive alcohol
Excessive weight
Viral hepatitis

21
Q

Portal hypertension cause

A

Commonly cirrhosis

22
Q

Portal hypertension causes

A

Splenomegaly
Ascites
GI varices
Encephalopathy
Captu Medusae
Hematemesis
Melena

23
Q

Causes of Hepatic Encephalopathy

A

Acute and chronic liver disease
Elevated ammonia and metabolic abnormalities

24
Q

Hepatic Encephalopathy Treatment

A

Antibiotics
Lactulose (may give diarrhea)
Ammonia lowering therapy
Liver transplant (skin breakdown)
Avoid hard exercise

25
Alcohol related liver disease Clinical Manifestations
Nausea, vomiting ab pain Anorexia, fever, weight loss Jaundice, Ascites, cognitive impairment to coma
26
Alcohol related disease treatment
Abstinence Nutritional support/vitamins Fluids
27
Causes of Hepatitis
Viral Chemical/toxic (alc, acetaminophen) Autoimmune disorders
28
Chronic Hepatitis common causes
Alcohol Hepatitis B and C
29
Chronic Hepatitis can lead to
Cirrhosis and hepatocellular carcinoma
30