2.2 Part 2 Flashcards
Profound Immunosuppression leads to
Opportunistic infections
Secondary neoplasms
Neurologic manifestations
CD4 T cells stimulate
Other immune cells to fight infection
(Macrophages, B lymphocytes, T lymphocytes)
HIV weakens immune system by
Destroying CD4 cells and hijacking them and forcing it to make copies of HIV
HIV
Presence of the human immunodeficiency in a persons bloodstream
AIDS
Set of symptoms and illnesses that develop as a result of advanced HIV infection that has destroyed the immune system
AIDS criteria
CD4 T cell count very low (< 200)
Opportunistic infection (sarcoma, fungal infection)
Where is HIV found
Blood
Semen
Vaginal/cervical secretions
Rectal secretions
Breast milk
HIV transmission occurs by
Exchange of body fluids
Sexual transmission
IV drug abuse
Mother to infant
Blood transfusions
Accidental needle sticks
Stage 1 of HIV
Acute HIV infection
- flu like illness within 1-6 weeks after infection
Stage 2 HIV
Clinical Latency
- asymptomatic HIV infection; can last a decade or longer
Stage 3 HIV
Most severe phase over time
HIV destroys so many cells the body cant fight off infections or disease
Decrease in CD4 cells
AIDs involvement
Immunodeficiency with opportunistic infections and unusual malignancies
- kaposi sarcoma (25% develop)
AIDs involvement Autoimmune
RA
AIDs involvement neurological dysfunction
Dementia
Encephalopathy
Peripheral neuropathies
Medical Management Prevention
Education
Reduction/eliminate risky behavior
Medical Management Diagnosis
Nuclei Acids Tests
Antigen/Antibody Tests
Supplementary lab testing
Medical Management Treatment Goals
Highly active antiretroviral therapy ASAP
Keep patient as healthy as possible
Reduce changes of HIV spread
Medical Management Prognosis
Combination therapy is extending lives
Therapist Implications
Prevention of Transmission
Greater risk in wound healing capacity
If exposed evaluate
Source and begin post exposure prophylaxis
Fibromyalgia Incidence
20-55 years
Fibromyalgia Risk Factors
Prolonged anxiety, stress, trauma
Rapid steroid withdrawl, hypothyroid, viral/non viral infections, depression
Fibromyalgia
Idiopathic, non inflammatory, central pain processing syndrome, characterized by chronic, diffuse musculoskeletal pain
Often associated with neuropsychological symptoms and variety of somatic complaints
Fibromyalgia commonly associated with
Hypothyroid, RA, SLE, chronic fatigue syndrome
Medical Management Diagnosis Fibromyalgia
Widespread pain index (WPI) + Symptom Severity Score (SSS)
Symptoms for >/= 3 months
No other diagnosis
Medical Management Treatment Fibromyalgia
Patient Education
Stress management and work simplification
Medications
PT
