3.7 Development of multicellular organisms Flashcards

1
Q

Genome of all cells in an organism are

A

identical

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2
Q

Expression of genes is

A

different

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3
Q

What are the 4 major phases in development?

A

Cell division, cell differentiation, cell interaction. cell migration

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4
Q

Genes expressed by cell depend on what?

A

Environement both present and past

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5
Q

Homologous proteins are functionally what?

A

interchangeable

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6
Q

What is a blastula?

A

Ball of cells surrounding a hollow cavity

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7
Q

What is a gastrula?

A

Blastula that undergoes rearrangements, 3 major layers.

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8
Q

What does the blastula consist of ?

A

Sheet of epithelial cells

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9
Q

What is the ectoderm?

A

previrsor of nervous system and epidermis

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10
Q

What gives rise to the ectoderm?

A

the blastula

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11
Q

What gives rise to the endoderm?

A

ectoderm

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12
Q

The endoderm is the precursor of what 3 things?

A

Gut, lung, liver

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13
Q

What gives rise to the mesoderm?

A

The group of cells that move inbetween ectoderm and endoderm

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14
Q

Mesoderm is precursor to what?

A

muscle and connective tissue

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15
Q

What the definition of gastrulation?

A

Transformation of the blastula into a layered structure with a gut.

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16
Q

What do fruit flys and humans have in common?

17
Q

What is the most important for development?

A

gene regulatory proteins

18
Q

What holds the instruction for producing a multicellular animal?

A

non coding regulatroy DNA

19
Q

What serve as binding sites for gene regulatory proteins?

A

Regulatory elements

20
Q

What sequence are similar in most organisms

A

coding sequences

21
Q

What sequences make one organism dif from another?

A

non coding sequences

22
Q

What comes first? Developmental decisions or differentiation?

A

Developmental decisions

23
Q

What are determined cells?

A

Cells that are fated to develop into a specialized cell type despite changes in environment

24
Q

What are completely undetermined cells?

A

Cells that can change rapidly due to alteration in environment

25
What are committed cells?
Cells that have some attributes of a particular cell type but can change with environment.
26
Position specific character of cell is called what?
positional value.
27
How can cells become different?
Asymmetric division
28
How can cells born the same can become dif?
Change in environment after birth
29
What is the most important environmental cues?
Signals from neighboring cells
30
What is inductive signaling?
Induction of a dif developmental program in select cells in a homogenous group leading to altered character
31
What are short range signals?
cell to cell contact
32
What are long range signals?
substances that can diffuse through the extracellular medium
33
What is a morphogen?
a long range inductive signal that imposes a pattern on a field of cells.
34
What 3 main factors are due to diversity in pattern?
Gene duplication, presence of other signals and previous experiences of the cell
35
What is the ultimate result of inductive events?
change in DNA transcription
36
Signaling pathways response depends on what two things?
spatial and temporal expression