第36章--大环内酯类与林可霉素类和多肽类抗生素 Flashcards

1
Q

大环内酯类抗生素对下述哪类细菌无效:

A

大肠杆菌、变形杆菌

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2
Q

对肺炎支原体、衣原体作用较强的药物是

A

罗红霉素

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3
Q

金葡菌引起的急、慢性骨髓炎,可选用的药物是:

A

克林霉素

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4
Q

大环内酯类药物有:

A
A.红霉素
B.罗红霉素
C.阿齐霉素
D.麦迪霉素
E.多沙霉素
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5
Q

红霉素的作用机制是:

A

A.与细菌核蛋白体的50S亚基结合,抑制细菌蛋白质合成

C.与细菌核蛋白体70S始动复合物结合,抑制细菌蛋白质合成

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6
Q

对支原体肺炎有效的药物是

A

C.红霉素

D.麦迪霉素

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7
Q

红霉素的主要不良反应有:

A

A.胃肠道反应
B.肝损害
D.静注可致静脉炎

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8
Q

与青霉素合用时可产生拮抗作用的药物是:

A

A.红霉素

E.四环素

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9
Q

作用于细菌静止期的杀菌药是:

A

B.链霉素
C.庆大霉素
E.多粘菌素

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10
Q

速效抑菌药为:

A

C.阿齐霉素
D.罗红霉素
E.四环素

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11
Q

慢效抑菌药

A

D.磺胺嘧啶

E.甲氧苄啶

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12
Q

红霉素主要用于:

A

A.耐青霉素的金葡菌感染
B.青霉素过敏者
C.军团菌病

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13
Q

治疗金黄色葡萄球菌所致慢性骨髓炎的药物为

A

A.青霉素类+林可霉素
B.头孢他定+林可霉素
D.头孢孟多+环丙沙星

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14
Q

阿齐霉素的特点是:

A
A. 对流感杆菌、淋球菌抗菌活性高
B. 不易被胃酸破坏 
C. 生物利用度高
D  t1/2延长              
E. 不良反应较红霉素少见
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