第17章--抗精神失常药 Flashcards

1
Q

氯丙嗪治疗精神病的机理是

A

阻断中脑边缘系统和中脑皮层通路的多巴胺受体

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2
Q

小剂量氯丙嗪镇吐作用的部位是

A

延脑催吐化学感受区

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3
Q

氯丙嗪对正常人产生的作用是

A

安定、镇静和感情淡漠

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4
Q

吩噻嗪类药物引起锥体外系反应的机制是阻断

A

黑质-纹状体通路的多巴胺受体

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5
Q

可减少外周多巴胺生成,使左旋多巴较大量进入脑内的药物是

A

巴脱羧酶抑制剂

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6
Q

氯丙嗪引起的帕金森综合征是由于:

A

阻断黑质-纹状体通路的D2受体

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7
Q

氯丙嗪引起口干、便秘、视力模糊是由于

A

阻断M胆碱受体

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8
Q

氯丙嗪引起体位性低血压是由于

A

阻断α-肾上腺素受体

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9
Q

氯丙嗪抗精神病的作用机制是由于:

A

阻断中脑-边缘叶及中脑-皮质通路的D2受体

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10
Q

氯丙嗪对哪些呕吐有效

A

A. 癌症
B. 放射病
D. 顽固性呃逆

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11
Q

氯丙嗪的中枢药理作用包括

A

A. 抗精神病
B. 镇吐
D. 降低体温
E. 加强中枢抑制药的作用

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12
Q

氯丙嗪的锥体外系反应有

A

A. 急性肌张力障碍
C. 静坐不能
D. 帕金森综合症
E. 迟发性运动障碍

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13
Q

氯丙嗪体内过程具有的特征是:

A

A. 口服与注射均易吸收
D. 易透过血脑屏障,脑组织分布较广,浓度高
E. 主要经肝微粒体酶代谢

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