2.1 MS Intro

Question 1

What are the 2 classifications of autoimmune disease?

Answer 1

Systemic = where the entire body is affected

Organ Specific = where the organ targeted by the immune system is based on receptor sensitivity.

Question 2

What are cardinal symptoms of MS as defined by Charcot?

Answer 2

Intention tremor, scanning, speech, nystagmus

Question 3

What specific aspects of the body are attacked in multiple sclerosis?

Answer 3

Myelin nerve coating, oligodendrocytes and nerve fibers in the CNS

Question 4

What are the functions of myelin in the body?

Answer 4

Myelin serves as an insulator to the nerves and aids in the transmission of action potentials.

Question 5

What systems are affected with MS?

Answer 5

CNS

Question 6

What lab/imaging is done to assist in diagnosing MS?

Answer 6

T-2 weighted MRI

Question 7

What does the sagittal view of an individual with MS look like?

Answer 7

There are lesions in the form of white plaque

Question 8

Clinically Isolated Syndrome

Answer 8

isolated event of inflammatory demyelination that could progress to other forms if left unchecked

Question 9

Relapsing Remitting

Answer 9

CIS becomes active and new MRI indicate new lesions or symptoms then it is termed relapsing remitting

Most common there is near baseline recovery

Question 10

Secondary Progressive

Answer 10

Progression and worsening of symptoms occurs after the relapse attack

Question 11

Primary Progressive

Answer 11

Continuous worsening of symptoms from the onset of the first attack. Patients can have relapse attacks throughout the progression