2. genel cerrahi Splenic Diseases

Question 1

who did the first splenectomy?

Answer 1

Adriano Zaccavello

Question 2

Spleen ne zaman oluşmaya basşlar

Answer 2

Gestational 12th

Question 3

Spleen Derivate from?_

Answer 3

from mesoderm

Question 4

Accessory Spleen seen in?

Answer 4

Accessory Spleen : %20 of population

Question 5

imp things about Physical Examination of spleen

Answer 5

Traube
*
Kehr’s Sign

Question 6

Hyposplenism?

Answer 6

Defective or absent spleen

Question 7

Hypersplenism is?

Answer 7

*Defined as the presence of one or more
cytopenias ,

Question 8

Splenomegaly is?

Answer 8

500g or greater in 15cm
* If greater than
1kg or 22cm in length, then its termed massive
splenomegaly.

Question 9

Imaging Methods inAssessing Size andPathology

Answer 9

USG
*
Computerized Tomography
*
X ray
*
Magnetic Rezonans
*
Angiography
*
Tecnesium 99m Radiosintigraphy

Question 10

Benign Hemathologic Diseases Of Spleen are?

Answer 10

Hereditary Spherocytosis
*

Enzymatic Defects

Pyruvate Kinase Enzyme Deficiency

G6PDH Enzyme Deficiency

Warm Type Autoimmun Hemolytic Anemia

Hemoglobinopathies

Sickle Cell Anemia , Talasemia

Platelet Disorders
*
ITP and TTP

Question 11

Malignant Diseases of Spleen caused by white white blood cell disorders are

Answer 11

Hairy Cell Leucemia
*
Hodgkin’s Disease
*
Non Hodgkin Lymphoma
*
Chronic Lymphocytic Leucemia

Question 12

Malignant Diseases of Spleen caused by Myeloproliferative Neoplasms are

Answer 12

Chronic Myeloid Leucemia

Acute Myeloid Leucemia

Chronic Myelomonocytic Leucemia

Essential Trombocytosis

Polisitemia Vera

Myelofibrosis

Question 13

Storage Diseases and Infiltrative Disorders of spleen

Answer 13

Gaucher’s Disease
*
Niemann Pick Disease
*
Amyloidosis
*
Sarcoidosis

Question 14

other imp disease of spleen

Answer 14

Splenic Artery Aneurism
*
Portal Hypertension
*
Felty Syndrome
*
Wandering Spleen

Question 15

The Most Common İndications Of Splenectomy?

Answer 15

Splenic rupture (trauma)

Question 16

The most common indications for elective splenectomy

Answer 16

Malignancy and hematologic autoimmune disorders ,
*
Idiopathic thrombocytopenic purpura (ITP)

o autoimmune hemolytic anemia

Question 17

What is Hereditary spherocytosis (HS) is the most common type of hemolytic anemia for which splenectomy is indicated

Answer 17

Hereditary spherocytosis (HS) is the most common

Question 18

What is most common glycolytic defect causing congenital non spherocytic hemolytic anemia

Answer 18

Pyruvate kinase (PK) deficiency

Question 19

The most common red blood cell enzyme deficiency overall is …….. deficiency .

Answer 19

G6PD

Question 20

Splenectomy is indicated for patients with excessive
transfusion requirements ,………

Answer 20

(>200 mL/kg per year)

Question 21

The low platelet count stems from premature removal of platelets opsonized by ………………autoantibodies produced
in the spleen.

Answer 21

antiplatelet immunoglobulin G

Question 22

Petechial hemorrhages in the lower extremities are the most common presenting sign of

Answer 22

Thrombotic Thrombocytopenic Purpura

Question 23

What happens at Thrombotic Thrombocytopenic Purpura

Answer 23

Abnormal platelet clumping occurs in arterioles and
capillaries, reducing the lumen of these vessels and
predisposing the patient to microvascular thrombotic
episodes.

Question 24

HCL is characterized by ……

Answer 24

splenomegaly, pancytopenia, and large numbers of abnormal lymphocytes in the bone marrow.

Question 25

WhgaT İS THE Proliferation of any one of the three predominant lymph cell types Non Hodgkin’s Lymphoma,?

Answer 25

natural killer cells, T cells, or B cells

Question 26

WHİCH İNFECTİONS CAN CAUSE SPLENO MEAGALY

Answer 26

Epstein Barr virus or cytomegalovirus infection

spontaneous splenic rupture in both
adults and children.

Question 27

What is the name of this disease thatrr cause parasitic cyst of spleen

Answer 27

Echinococcus species.

Question 28

what is Felty syndrome (FS

Answer 28

is a rare extra-articular manifestation of seropositive rheumatoid arthritis (RA) characterized by RA, neutropenia, and splenomegaly. Severe or recurrent infection is of particular concern due to neutropenia, especially in the skin and respiratory system.

Question 29

What is Wandering Spleen

Answer 29

The spleen “floats” inside the abdominal cavity

Due to an anomaly duringembryogenesis
ü,

Presentation: acute abdomen

Not normally attached toadjacent viscera in the splenicfossa.

This may lead to splenictorsion and infarction.*Splenopexy or splenectomymay be required