1. genel cerrahi BLOOD TRANSFUSION Op.

Question 1

What is Danger zone for hemolysis

Answer 1

> 4 unit day is massive transfusion

Question 2

.

Answer 2

ç

Question 3

Changes occurring in whole blood during the waiting period include:

Answer 3

Increased intracellular ADP

Decreased levels of 2,3 DPG

Progressive increases in lactate, potassium, and ammonia

Blood becomes acidic.

Question 4

why use Leukocyte Reduced?

Answer 4

Preferred in immunosuppressed patients

Prevents:

Febrile and non febrile transfusion reactions

Alloimmunization with HLA Class 1 antigens,

Platelet transfusion refractoriness

Transmission of CMV infection

Question 5

Fresh Frozen Plasma neden önemli

Answer 5

Vitamin K bağımlı faktörlerin doğal kaynağı ve faktör 5’in tek kaynağıdır.

Kanayan hastalarda kullanımı giderek
artmaktadır

Donmuş olarak saklanır. Eritilince 5
güne kadar depolanabilir.

Question 6

what is Cryoprecipitate?

Answer 6

frozen plasma proteins include
fibrinogen
factor 8 13 and Von Willerbrand

should 1-6 derece

Question 7

what are the Blood Transfusion Indications?

Answer 7

Increasing Oxygen Transport Capacity

Treatment Of Anemia 7 9 g/dL does not have a negative impact on mortality

Volume Resuscitation MOST İMP

Question 8

Blood Transfusion Reactions

Answer 8

1. Hemolytic Reactions

2 Non Hemolytic Reactions

3 Allergic Reactions

4 Respiratory Reaction s

Question 9

What is the Hemolytic Reactions caused by transfusion?

Answer 9

Occurs due to technical errors.

Acute Hemolysis

ABO incompatiblity leeds to %6 death rate

DIC (Disseminated Intravascular Coagulation) can develop ::: Factor 12

Acute renal failure

Question 10

Delayed Hemolytic Transfusion Reactions?

Answer 10

Occurs within 2 10 days.

Non ABO antibodies develop against

Low titers of antibodies are present.

chest pain ext…

Diagnosis is confirmed by a positive Coombs test.

Question 11

what is imp about Non Hemolytic Reactions at transfusion?

Answer 11

Body temperature has increased by more than 1 degree Celsius.

Cytokines and antibodies in the recipient and donor blood play a role. Gr Sepsis?,

Symptoms: chills, tachycardia, hypotension, abdominal pain, vomiting, and diarrhea.

Treatment: Oxygen and antiadrenergic agents, and antibiotics are treatment options

Question 12

what is imp about Allergic Reactions at transfusion?

Answer 12

1% of all transfusions.

Reactions are mild.

Urticaria, flushing.

Anaphylactic shock is rare.

due to antibody antigen hypersensitivity.

most common in FFP and platelet concentrates.

Treatment:
Antihistamin ic agent ,
steroid, epinephrine

Question 13

what is imp about Respiratory Complications at transfusion?

Answer 13

CVP measurement should be performed.

TRALI Syndrome: Transfusion Related Acute Lung Injury

It occurs 1 2 hours after transfusion.

The treatment is diuresis.

Question 14

Diseases transmitted through blood transfusion

Answer 14

Malaria (Plasmodium Malaria)

Chagas Disease

Brucellosis

CMV (Cytomegalovirus)

Hepatitis A, B, C

HIV (Human Immunodeficiency Virus)

Prion Diseases (Creutzfeldt Jakob Disease)