Zinc Flashcards

1
Q

whats the body distribution of zinc?

A

2-3g

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2
Q

where is zinc mainly located in the body?

A

liver, muscle, bone

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3
Q

where is there a small amount of zinc in the body?

A

eye and prostrate gland

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4
Q

what is brass an alloy of?

A

copper/zinc

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5
Q

what releases zinc to albumin and transferrin for transport to the rest of the body?

A

metallothionein

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6
Q

zinc is a constituent of how many enzymes?

A

60

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7
Q

what are the functions of zinc?

A

constituent of 60 enzymes, maintains integrity of skin, improves wound healing (with poor zinc status), necessary for taste, mobilizes vitamin A from liver, essential for reproduction and growth, helps prevent toxicity of other minerals

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8
Q

what does zincs function as a constituent of 60 enzymes do?

A

CO2 carrier, synthesis of DNA/RNA, breaks down alcohol

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9
Q

what does zinc do with its function in the synthesis of DNA/RNA?

A

zinc fingers (transcription), makes protein

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10
Q

what does zinc do with its function of skin integrity?

A

prevents dermatitis

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11
Q

when does zincs function of improving wounds work?

A

when zinc status is poor

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12
Q

why is zinc necessary for taste?

A

zinc proteins in saliva

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13
Q

what does zinc do with its function of mobilizing vitamin A from the liver?

A

zinc is component of retinol-binding protein, growth and differentiation of tissues

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14
Q

what does zinc do with its function in reproduction and growth?

A

bound to RNA as stabilizer (influences protein synthesis), if deficiency during pregnancy - not maintained or fetal malformation

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15
Q

what does zinc do with its function of preventing toxicity of other metals?

A

competition for absorption, lead and copper

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16
Q

what happens with a zinc deficiency?

A

impaired growth, lack of sexual maturation in males, dermatitis, hair loss

17
Q

what happens in early pregnancy with zinc deficiency of impairments in growth?

A

fetal malformation, miscarriage

18
Q

what happens in late pregnancy with zinc deficiency of impairments of growth?

A

retarded growth; decreased DNA and stress tolerance, increased aggression; impaired avoidance conditioning

19
Q

what happens in childhood with a zinc deficiency in impairments of growth?

A

retarded growth

20
Q

what happens in adolescence in zinc deficiency with impairments of growth?

A

retarded growth, delayed sexual maturation in males

21
Q

what is zinc essential for in the brain?

A

development and functioning of brain, zinc dependent enzymes and neurotransmitters play a role in the central nervous system, may in turn affect cognition

22
Q

what can zinc deficiency in animals lead to?

A

structural malformations in the brain, changes in enzymes and proteins important for neurotransmitters, behavioral problems (reduced attention, memory, ability to learn)

23
Q

what did human studies in zincs link to cognition say?

A

emerging research on human models supports a beneficial role for zinc in human cognitive development and functioning

24
Q

what are the details of zinc deficiency in older adults?

A

ages 65-90; dietary zinc linked to cognitive function, low levels of zinc in blood and brain tissues or patients with alzheimer’s

25
Q

what are the details of zinc and the common cold?

A

one study found lozenges decreased length of colds by 50% but no effect on fever, zinc as zinc gluconate was effective in 400 subjects but not zinc acetate, other studies show its no more effective than placebo (sugar pill)

26
Q

whats the RDI for zinc?

A

M (11 mg)

W (8 mg)

27
Q

whats the difference in zinc absorption from beef to cereal?

A

much higher absorption with beef

28
Q

what are the main food sources of zinc?

A

all protein foods except egg white; meats, oysters, legumes (poor availability)