Pyridoxal Flashcards

1
Q

is it a trace element, vitamin, or mineral? Pyridoxal

A

vitamin B6

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2
Q

what is its coenzyme form? Pyridoxal

A

Pyridoxal Phosphate PLP

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3
Q

what are its three functions? Pyridoxal

A

Protein, fat and carbohydrate metabolism; Breakdown of homocysteine; Synthesis of white blood cells & hemoglobin
that carries 02

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4
Q

why is it important that it Breakdowns homocysteine? Pyridoxal

A

Increased in cardiovascular disease, Alzheimer’s, Parkinson’s

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5
Q

because one its functions is: Synthesis of white blood cells & hemoglobin
that carries 02, what happens with a deficiency here? Pyridoxal

A

causes microcytic anemia

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6
Q

what are the three deficiency symptoms? Pyridoxal

A

Dermatitis, Mental retardation, Antibody impairment

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7
Q

what does the deficiency symptom of Dermatitis do? Pyridoxal

A

Atrophied taste buds

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8
Q

what does the deficiency symptom of Mental retardation do? Pyridoxal

A

 Convulsive seizures

 Infants ingesting auto-claved formula

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9
Q

what are the five clinical deficiency symptoms? Pyridoxal

A

 TB: Isoniazid  Nausea of pregnancy  Old oral contraceptives  Carpal tunnel syndrome
 Premenstrual syndrome, depression

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10
Q

what are the clincial deficiency symptom details of TB: Isoniazid? Pyridoxal

A

Anti-vitamin

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11
Q

how much is needed to eliminate the deficiency symptom of nausea? Pyridoxal

A

50 mg/d

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12
Q

how much of an increase in requirements is needed with the deficiency symptom of old oral contraceptives that made people nausitious? Pyridoxal

A

Increased requirement to 30 mgd

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13
Q

how does this help with the deficiency symptom of Premenstrual syndrome, depression? Pyridoxal

A

Converts tryptophan to serotonin

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14
Q

when does toxicity occur? Pyridoxal

A

2-6 g/2-40 months

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15
Q

what are the two toxicity symptoms? Pyridoxal

A

 Sensory neuropathy  Lesions of the skin

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16
Q

what causes toxicity? Pyridoxal

A

From dosing for premenstrual tension, carpal tunnel syndrome

17
Q

whats an excellent food source? Pyridoxal

A

muscle meats

18
Q

is it widely distributed? Pyridoxal

A

yes

19
Q

what food source is it not in? Pyridoxal

A

enriched flour

20
Q

what are the five main food sources? Pyridoxal

A

 Enriched cereals  Meat, poultry, fish  Starchy vegetables

21
Q

why is it important for tryptophan? Pyridoxal

A

Tryptophan can be converted to niacin