Wk9- The Lymphatic System

Question 1

The lymphatic system:

Comprised of Organs/tissues/nodes/vessels and lymph fluid

What are the three functions?

1. Drain excess i- fluid
2. Transport dietary -
3. Facilitate i- response (spleen)

Answer 1

1. Interstitial fluid
2. Lipids
3. Immune

Question 2

Lymphatic tissue /Organs/nodes/vessels

To?
Thy?
L- nodes 600
Sp?
Ly- tissue and vessels 
Heart
St? 
Large and small -

Answer 2

Tonsils 
Thymus 
Lymph nodes 
Spleen 
Lymphatic tissue 
Stomach 
Intestines

Question 3

Primary lymphatic organs:

Producing ?competent cells
? B? marrow
Thy?

Answer 3

Immuno competent
Red bone
Thymus

Question 4

Secondary lymphatic organs :

The majority of immune response occurs in
Lymph -
s?
? Nodules

Answer 4

Nodes
spleen
Lymphatic

Question 5

Lymph nodes: 
- shape
-00
Lymph flows through n- in - direction 
Acts as a f- for waste 
Facilitates anti-
Large numbers of - cells and - cells 
Involved in A- immunity

Answer 5

Bean
600
Nodes , 1 direction 
Filter 
Antigen 
T cells B cells 
Adaptive

Question 6

The spleen:

Great mass of lymphatic tissue
White pulp= ly? Ma? and dendritic cells (- and - cells)
Red pulp= blood filled veinous si?

Answer 6

Lymphocytes , macrophages (T and B cells)

Veinous sinuses

Question 7

Innate immunity: 1st and 2nd line defence

Present at birth
General in action

1. First line= barrier, prevents entry (skin/ sa?/ mu? membranes
2. Second line =inflammation and - , antimicrobial pr? and white blood cells

Answer 7

1. Skin, saliva, mucous

2. Fever, antimicrobial proteins

Question 8

Innate immunity: 2nd line

Phagocytes:
N- and m- 
Free circulation and migration via ?
Attracted to ? area
Adheres to microbe and ?
Merge with lysosomes and ?
Produce oxidants superoxide and ??

Answer 8

Neutrophils, macrophages 
Chemotaxis 
Infested 
Ingests 
Digest 
hydrogen peroxide

Question 9

Innate immunity: 2nd line

Inflammation= mast cells 
Causes pain= r? h? s? 
3 stages 
1. Vaso- and increased permeability of - - (h-)
2. Phagocytes accumulate via -
3. Enhanced t? repair

Answer 9

Redness, heat, swelling

1. Vasodilation , blood vessels (histamine)
2. Chemotaxis
3. Tissue

Question 10

Innate immunity: 2nd line

Fever:
Increased core temperature , greater than --degrees 
Caused by pyro?
Hypothalamus increases h?
Inhibits bacteria/ virus 
Increases effects of Int?
Increases metabolic ? to r?

Answer 10

38 degrees 
Pyrogens 
Heat 
Interferons 
Rate,repair

Question 11

2nd line : interferons

Antimicrobial proteins released by cells upon infection 
Destroys viral re?
Reduce p- synthesis 
Destroys --- in cells 
Major defence against - infection

Answer 11

Replication
Protein
RNA
Viral

Question 12

The complement system:

-0 plasma proteins in li? activated to complement immune response.
Increases inf? releases basophils and m- cells
Bind and facilitate =ph?
Form membrane attack in plasma membrane= ly?

Answer 12

30 , liver
Inflammation , mast cells
Phagocytosis
Lysis

Question 13

Natural killer cells: 2nd line

5 to– % of lymphocytes in blood
Bloodhounds: sniff out de? cells and d?
Release p- (perforate cell) and g- (digesting enzymes and death cells)

Answer 13

10%
Defective , destroy
Perforins
Granzymes