Wk 9- Infectious Microbial Agents Flashcards
What are the 4 main microorganism?
- F-
- P-
- B-
- V-
- Fungi
- Protozoa
- Bacteria
- Viruses
Microorganism classification:
Saprophages: live off dead and d? matter
Symbionts: live together with -
Commensals: live with and host and cause no harm
Parasites: live on/in another o? and cause p? conditions
decaying
host
organism, pathogenic
Fungi:
E- Uni cellular = ? Multicellular = ? Yeasts live in - environments ? are visible mycelium Infection = myc?
Eukaryotes Yeasts Moulds Aqueous Moulds Mycoses
Fungi mycoses:
Types of infections
- Su? : outermost surface layer skin
- C- : colonise in hair/skin/ nails
- Sub C-: entry via skin trauma
- Sy? : via spores, most dangerous
- Superficial
- Cutaneous
- Sub cutaneous
- Systemic
Protozoa:
Unicellular E- Very mobile Engulf small microorganisms - environments Ingested in contaminated food and drink (g-) Carried by insects
Eukaryotes
Aqueous
Giardia
Bacteria:
No nucleus= P-
No m- bound o-
External f- / pili for mobility
Bacteria in every habitat on earth
Prokaryotes
Membrane ,organelles
Flagella
Pathogenic bacteria:
E coli
Fast replication =1 to 1 - in 8 hours
Inhabits i-
Cause gastro-
million
Intestines
Gastroenteritis
Periodontitis: bacteria
Porphyromonas g?
Bacterial anti? and immune system
Immune cells release ROS( R? Oxygen sp?) super oxide and hydrogen peroxide to attack bacteria
ROS attacks host tissue and attracts more - cells
Gingivalis
Antigens
Reactive oxygen species
Immune
Viruses:
Sub microscopic entities
They are ultra cellular p- , NOT cells
No n? o? or cytoplasm
Replicate - host
Parasites
Nucleus, organelles
Inside
Virus / virion structure:
Viral DNA/RNA encapsulated pr? shell = capsid
Viral e? enable insertion into host DNA
Outer layer from host cell l? bilayer
Use hosts biochemical replication mechanism
protein
Enzymes
Lipid
Viral Haemagglutinins and Neuraminidase:
Haemagglutinins:
Anti? glycoproteins on viral s?
Binds virus to host cells
1- different H identified
Antigenic , surface
18
Viral H and N:
Neuraminidase:
E- on viral surface
Acts on infected cells surface to release viral progency
- different N’s
Enzymes
Release
9
Effects of viral infection:
L? = cell rupturing , cell swell, functions diminish Syncytia= cells form together into large multi n? mass
Lysis
Nucleated
Mutations to viral DNA/RNA:
Results in different viral s?
Difficult for treatment
Strains