Wet AMD

Question 1

Exudative AMD

Answer 1

manifestation of AMD with exudative changes at macula

leads to severe vision loss

Question 2

Accumulation of ________ in Wet AMD

Answer 2

extracellular fluid
blood
lipid exudates

Question 3

Fluid in Wet AMD comes from….

Answer 3

normal choriocapillaris thru defective Bruch’s
leaky choroidal NV
fluid not draining from RPE thru defective Bruch’s

Question 4

Choroidal Neovascularization

Answer 4

new blood vessel growth in RPE/ Bruch’s from choroid

leak fluid, blood, lipids

Question 5

Symptoms of Exudative ARMD

Answer 5

sudden dramatic loss of vision in one eye

dark spot in vision

Question 6

Signs of Exudative AMD

Answer 6

accumulation of subretinal fluid and drusen
RPE detachments or tears
CNV
fibrovascular scarring at macula

Question 7

Serous PED

Answer 7

dome shaped elevation

Question 8

Fibrovascular PED

Answer 8

irregular elevation

Question 9

Drusenoid PED

Answer 9

shallow pale areas with scalloped borders

Question 10

Hemorrhagic PED

Answer 10

dark red dome with well defined outline

Question 11

RPE Tear

Answer 11

pale crescent where RPE missing next to darker area where it is bunched up

Question 12

Classic CNV Membranes

Answer 12

well defined membranes

subretinal

Question 13

Occult CNV Membranes

Answer 13

borders not fully defined

sub-RPE

Question 14

Fibrovascular Scarring

Answer 14

disciform scarring at macula as end result of wet AMD

Question 15

Mx of Wet AMD

Answer 15

refer to retinal specialist

anti-VEGF

Question 16

Macugen

Answer 16

first anti-VEGF

better than laser, but equal to photodynamic therapy

Question 17

Lucentis

Answer 17

Anti-VEGF
halts vision loss and can improve vision
$2000 per shot

Question 18

Avastin

Answer 18

Anti-VEGF
not FDA approved
off label
$50 per shot

Question 19

Eylea

Answer 19

newest anti-VEGF

lasts longer

Question 20

SE of Anti-VEGF Injections

Answer 20

RD
cataract
RPE tears
infection
increase of stroke risk