Inflammatory Diseases 2 Flashcards
Ocular Sarcoidosis
granulomatous inflammatory condition involving primarily lymph nodes, lungs, and eyes
Presentation of Ocular Sarcoidosis
in colder climates and African Americans
anterior uveitis/ nodules
multifocal granulomas around ON, retina, choroid
snowballs; candlewax drippings
Diagnosing Ocular Sarcoidosis
definite- biopsy of lungs and conjunctival bumps
presumed- chest radiograph
Tx of Ocular Sarcoidosis
topical steroids for anterior uveitis
systemic steroids for posterior uveitis
Behcet’s Disease
idiopathic vasculitis with recurrent oral and genital ulceration
systemic- aneurysms, coronary artery disease, venous thrombosis
Presentation of Behcet’s Disease
anterior uveitis, mobile hypopyon
vitritis
retinal vasculitis, frequently occluded
Tx of Behcet’s Disease
topical steroids for ant uveitis
systemic steroids for post seg issues
immunosuppresants
VKH Syndrome
Vogt-Koyanagi-Harada
autoimmune inflammatory condition affecting melanin containing tissue- Uveal Tract in eye
Hispanic and Japanese
Symptoms of VKH
decreased vision
eye pain
red eyes
light sensitivity
Signs of VKH
bilateral uveitis, can be granulomatous
vitritis, papillitis, exudative choroiditis
elevated macula
sunset glow fundus
Systemic Signs of VKH
neurological
auditory
integumentary- poliosis
Tx of VKH
long term steroids
Sympathetic Ophthalmia
bilateral granulomatous panuveitis following penetrating ocular trauma
injury to one eye cause inflammatory rxn in other eye
Signs of Sympathetic Ophthalmia
bilateral granulomatous anterior uveitis
bilateral choroidal and sub-RPE infiltrates
Tx for Sympathetic Ophthalmia
long term steroids