Malignant Tumors Flashcards
Retinoblastoma
incomplete differentiation of retina cells
in kids
fatal if not treated
Presentation of Retinoblastoma
in early childhood
white pupil- leukocoria
white mass in retina
strabismus common
Treatment of Retinoblasoma
photocoagulation
cryotherapy
chemotherapy
Choroidal Melanoma
malignant tumor of choroidal melanocytes- version of nevus
can cause death if spreading to other organs
Presentation of Choroidal Melanoma
50-60 normally pigmented (brown/ gray) dome shaped subretinal elevation; can be amelanotic and flat clumps of orange pigment (lipofuscin)
Diagnosis of Choroidal Melanoma
Thickness 2-3mm Fluid, subfoveal Symptoms present Orange pigment Margins indistinct
Tools to aid diagnosis of Choroidal Melanoma
angiography, ultrasound, MRI
biopsy
Treatment of Choroidal Melanoma
systemic investigation- liver
irradiation- brachytherapy
Secondary tumors of the eye normally originate……
in lungs or breast
Presentation of Choroidal Metastases
usually affect macula
flat creamy-white placoid lesion
serous RD common
Diagnosis of Choroidal Metastases
history of primary tumor
ultrasound, angiography
Treatment of Choroidal Metastasis
most dead w/in 1 year
systemic eval by oncologist
ocular treatment only for symptoms
Intraocular Lymphoma
malignant proliferation of lymphocytes (WBCs) in eye
from primary CNS lymphoma
most develop CNS symptoms before or after discovery
Presentation of Intraocular Lymphoma
older patients w/ unilateral floaters/ blur- becomes bilateral
severe vitritis not clearing w/ steroids and no CME
multiple yellow-white subretinal infiltrates
Diagnosis of Intraocular Lymphoma
recalcitrant posterior vitritis
vitreous biopsy
lumbar puncture
