Benign Tumors

Question 1

Congenital Hypertrophy of RPE

CHRPE

Answer 1

benign neoplasm of RPE

typical or atypical

Question 2

Typical CHRPE

Answer 2

common
not associated with systemic condition
unilateral and nonprogressive

Question 3

Atypical CHRPE

Answer 3

rare
associated with familial adenomatous polyposis (FAP)
bilateral
lesions scattered throughout fundus
elongated oval with tail

Question 4

Solitary Typical CHRPE Presentation

Answer 4

darkly pigmented, flat, round lesions with well defined borders
hypopigmented lacunae w/in lesion
larger- 1-6mm

Question 5

Grouped Typical CHRPE Presentation

Answer 5

smaller- .1 - 2mm
in same quadrant
dark- bear tracks
non-pigmented- polar bear tracks

Question 6

Familial Adenomatous Polyposis

FAP

Answer 6

genetic disease causing precancerous colorectal polyps in teens
progresses to cancer in all if untreated

Question 7

Mx of CHRPE

Answer 7

monitor for typical

refer to GI specialist if atypical

Question 8

Choroidal Nevus

Answer 8

benign tumor of choroidal melanocytes

can become malignant

Question 9

Signs of Choroidal Nevus

Answer 9

oval/ round flat lesion w/ indistinct borders

slate gray

Question 10

Diagnosis of Choroidal Nevus

Answer 10

red free filter- disappears

Question 11

Mx of Choroidal Nevus

Answer 11

document- photos and OCT

watch for size/ thickness increase, or for orange coloration

Question 12

Choroidal Melanocytoma

Answer 12

benign tumor of choroidal melanocytes near ON
variant of choroidal nevus
more in dark skinned ppl
can become malignant

Question 13

Combined Hamartoma of Retina and RPE

Answer 13

rare congenital tumor composed of various cell types from retina and RPE
near optic disc

Question 14

Signs/ Symptoms of Combined Hamartoma

Answer 14

visual distortion from dragging of macula or disc
exudation(NV for tumor)- more likely to cause vision problems
tumor near disc

Question 15

Choroidal Hemangioma

Answer 15

benign choroidal vascular tumor
circumscribed or diffuse
kids to young adults
normally asymptomatic

Question 16

Diffuse Choroidal Hemangioma

Answer 16

in patients with Sturge-Weber syndrome

neurological consult needed

Question 17

Capillary Hemangioma

Answer 17

benign vascular tumor of retinal capillary bed

sight and life threatening associations

Question 18

Patients with Capillary Hemangioma must be tested for

Answer 18

Von Hippel- Lindau disease- genetic cancer syndrome

Question 19

Retinal Cavernous Hemangioma

Answer 19

benign vascular tumor w/ clusters of retinal venous aneurysms
“grape cluster”

Question 20

Racemose Hemangioma

Answer 20

congenital malformation of retinal vasculature
asymptomatic
sometimes accompanied by similar lesions of brain or jaw

Question 21

Retinal Vasoproliferative Tumor

VPT

Answer 21

gliovascular lesion found after decrease vision from ERM or macular edema
yellow-red peripheral mass (most inf-temp)
major exudation common

Question 22

Mx of Retinal Vasoproliferative Tumor

Answer 22

monitor if tumor does not leak

cryotherapy, laser photocoagulation, PDT

Question 23

Retinal Astrocytoma

Answer 23

benign congenital tumor of retinal glial cells
asymptomatic
associated with tuberous sclerosis (Bourneville disease)

Question 24

Choroidal Osteoma

Answer 24

benign tumor of mature bone in choroid
at or near disc
asymptomatic unless macula affected

Question 25

Signs of Choroidal Osteoma

Answer 25

initially orange, later yellow-white lesion
atrophy of overlying RPE
CNV- only part treated