weight loss Flashcards
select drugs that cause weight gain
- antipsych (high w/ clozapine, olanzapine, respirodlone, quetiapine)
- diabetes drugs (insulin, SU/meg, tzds)
- divalproex/valporic acid
- gaba, pregab
- lithium
- mirtazapine
- steroids
- TCAs (amitriptyline, nortriptyline)
- conditions: hypothyroidism
otc weight loss
- bitter oranges …
- caffeine
- guarana
- green tea powder extracts
key drugs that can cause weight loss
ADHD
bupropion
GLP-1 agonists (exenatide, liragtuide)
Pramlintide
roflumilast
SGLT inhibitors (canagliflozin, empagliflozin)
topiramate
conditions: hyperthyroidism, celiac disease, IBS
Prescription weight loss drugs: avoid or use caution
prego
avoid all weight loss drugs
prescription weight loss drugs: avoid or use caution
hypertension
avoid: contrave
Caution: qsmia- monitor HR (contains phentermine)
prescription weight loss drugs: avoid or use caution
depression
cation in young adults and adolescents
contrave- suicide risk
prescription weight loss drugs: avoid or use caution
seizures
avoid: contrave- lowers seizure threshold
caution: qysmia- must tapper off slowly if used (contains topiramate)
prescription weight loss drugs: avoid or use caution
taking opioids
avoid: contrave- blocks opioid receptors (contains naltrexone)
phentermine
sympathomimetic stimulation (appetite suppressants)
topiramate: increase satiety and decrease appetite, possibly by GABA
Qysmia
phentermine/ topiramate ER
REMs drug due to tratogenic risk
contrave
naltrexone/bupropion
decrease food cravings
MOA - 14 day washout remember…
liraglutide
Saxenda
victoza- for diabetes
- GLP-1 agonist
semaglutide
wegovy
ozempic for diabeteis
- GLP-1 agonist
adipex
Phentermine
- short-term 12 weeks… to “jump-start” a diet
