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NAPLEx > tox > Flashcards

tox Flashcards

1
Q

anticholinergics

A

atropine, diphenhydramine, dimenhydrinate, scopolamine, atropa belladonna (dealdy nightshade), jimson weed:

tx w/ primarily supportive care, rarely physostigmine

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2
Q

apixaban, rivaroxaban

A

Andexxa

andexanet alfa

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3
Q

dabigatran

A

indarucizumab (praxabind)

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4
Q

warfarin

A

phytonadione (vitamin K)

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5
Q

heparin, LMWH

A

protamine

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6
Q

warfarin, factor Xa inhibitors

A

prothrombin complex concentrate (Kcentra)

II, VII, IX, X

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7
Q

antipsych

A

primarily supportive care, benztropine can be given for dystonia, and bicarb if QRS- interval widening

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8
Q

benzos

A

flumazenil

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9
Q

beta-blockers

A

glucagon (if unresponsive to symptomatic tx)

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10
Q

Ca channel blockers

A

Ca

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11
Q

cyanide: smoking inhalation, nitroprusside in high doses/long durations/renal impairment

A

hydroxocobalamin (cyanokit)
sodium thiosulfate + sodium nitrate (nithiodote)

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12
Q

digoxin

A

digoxin immun fag (digifab)

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13
Q

ethanol

A

thiamine (B1) to prevent Wernicke’s encephalopathy
can cause an increase anion gap

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14
Q

heavy metals: arsenic, copper, gold, lead, mercury, thallium

A

dimercaprol: arsenic, gold mercury

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15
Q

Hydrocarbons: petroleum products

A

do not induce vomiting: keep pt NPO due to aspiration risk

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16
Q

insulin, or other hypoglycemic

A

dextrose (do not admin if pt unconscious)
glucagon when IV or oral dextrose can not be admin
sulfonylurea-induced hypo: octreotide (Sandostatin)

17
Q

Isoniazid

A

pyridoxine (vitamin B6)

18
Q

iron and aluminum

A

deferoxamine (desferal)

19
Q

methotrexate

A

leucovorin (folinic acid), levoleucovorin (fusilev)

20
Q

meostigmine, pyridostigmine

A

pralidoxime (protopam)

21
Q

nicotine

A

supportive care, atropine for symptomatic bradycardia, benzo for seizures

22
Q

salicylates

A

salicylates are acidic, sodium bicarb

23
Q

stimulant overdose

A

supportive care for agitation or seizures (benzo)

24
Q

toxic alcohol: ethylene glycol (antifreeze), methanol

A

can increase anion gap
fomepizole is prefered, ethanol 2nd line

25
Q

TCAs

A

can quickly cause fatal arrhythmias
sodium bicarb to decrease widening of QRS complex

26
Q

valproic acid or topiramate-induced hyperammonemia

A

levocarnitine (carnitor)

27
Q

organophosphate over dose
symptoms

A

SLUDD
salivation
lacrimation
urination
diarrhea
defecation

28
Q

organophosphate over dose
tx

A

atropine blocks effects of acetylcholine

pralidoxime (protopam): reactive cholinesterase

can be used in combo: DuoDote

29
Q

organophosphate over dose
cause

A

are in pesticides. people working on farms are at risk

30
Q

animal bites

A

rabies vax + human rabies immuno globulin

31
Q

black widow spider bites
scorpion sting

A

antivenin

32
Q

snake bites

A

crotalidae polyvalent immune FAB (CroFab) for copperhead and rattlesnake bites

NAPLEx (75 decks)

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