tox Flashcards
anticholinergics
atropine, diphenhydramine, dimenhydrinate, scopolamine, atropa belladonna (dealdy nightshade), jimson weed:
tx w/ primarily supportive care, rarely physostigmine
apixaban, rivaroxaban
Andexxa
andexanet alfa
dabigatran
indarucizumab (praxabind)
warfarin
phytonadione (vitamin K)
heparin, LMWH
protamine
warfarin, factor Xa inhibitors
prothrombin complex concentrate (Kcentra)
II, VII, IX, X
antipsych
primarily supportive care, benztropine can be given for dystonia, and bicarb if QRS- interval widening
benzos
flumazenil
beta-blockers
glucagon (if unresponsive to symptomatic tx)
Ca channel blockers
Ca
cyanide: smoking inhalation, nitroprusside in high doses/long durations/renal impairment
hydroxocobalamin (cyanokit)
sodium thiosulfate + sodium nitrate (nithiodote)
digoxin
digoxin immun fag (digifab)
ethanol
thiamine (B1) to prevent Wernicke’s encephalopathy
can cause an increase anion gap
heavy metals: arsenic, copper, gold, lead, mercury, thallium
dimercaprol: arsenic, gold mercury
Hydrocarbons: petroleum products
do not induce vomiting: keep pt NPO due to aspiration risk
insulin, or other hypoglycemic
dextrose (do not admin if pt unconscious)
glucagon when IV or oral dextrose can not be admin
sulfonylurea-induced hypo: octreotide (Sandostatin)
Isoniazid
pyridoxine (vitamin B6)
iron and aluminum
deferoxamine (desferal)
methotrexate
leucovorin (folinic acid), levoleucovorin (fusilev)
meostigmine, pyridostigmine
pralidoxime (protopam)
nicotine
supportive care, atropine for symptomatic bradycardia, benzo for seizures
salicylates
salicylates are acidic, sodium bicarb
stimulant overdose
supportive care for agitation or seizures (benzo)
toxic alcohol: ethylene glycol (antifreeze), methanol
can increase anion gap
fomepizole is prefered, ethanol 2nd line
