Dyslipidemia Flashcards
atorvastatin
Lipitor
- statin
atorvastatin + amlodipine
caduet
- statin
fluvastatin
lescol- taken in evening
lescol XL
lescol discontinued but name still used in practice
- statin
lovastatin
altoprev- extended release, taken at bedtime
Mevacor- brand discontinued but name still used in practice
Lovastatin- immediate release is taken with evening meals
- statin
Pitavastatin
Livalo, Zypitamag
Pravastatin
Pravachol
Rosuvastatin
Crestor, Ezallor Sprinkle
consider 5mg starting dose in Asian patients - exposure 2xhigher
Simvastatin
Zocor, Flopid
do not initiate 80mg dose
Simvastatin + ezetimibe
Vytorin
ezetimibe
Zetia
inhibits absorption of cholesterol in the small intestine
Alirocumab
Praluent
-PCSK9 inhibitor
Evolocumab
Repatha, Repatha SureClick, Pushtronex
-PCSK9 inhibitor
Cholestyramine
Prevalite, Questran, Questran Light
- bile acid sequestrants
Colesevelam
Welchol
also approved for glycemic control in type 2 DM
- bile acid sequestrants
Colestipol
Colestid
- bile acid sequestrants
Fenofibrate
Antara, Ticor, Trilipix, Fenoglide, Fibricor, Lipofen, Triglide, genrics
- fibrates
gemfibrozil
lopid
- fibrates
Niacin
IR (crystalline)- Niacor,
ER- Nispan- best less flushing and less hepatotoxicity
CR/SR- Slo-Niacin
CR/SR have more hepatoxicity
Omega- 3 Acid Ethyl Esters
Lovaza
- fish oil
Icosapent ethyl
Vascepa
- fish oil
Lomitapide
juxtapid
Pharmacist Rock At Saving Lives & Preventing Fatty deposits
pitavastatin 2mg
rosuvastatin 5mg
Atorvastatin 10mg
Simvastatin 20mg
Lovastatin 40mg
Pravastatin 40mg
Fluvastatin 80mg
managing myalgias
do not use simva 80mg/ day
do not use lopid and statin together
G <3 PACMAN
do not use with simva and lova
grapefruit
<3
protease inhibitors
Azole antifungals
C- cyclosporine, cobicistat: max rosuv 5/day w/ cyclo, atorva 20/day with cobicistat
Macrolides (except azithro)
Amiodarone: max simva 20/day, lova 40/day
Non-DHP CCs: max simva 10/day, lova 20/day
simva/amlodipine
max 20mg/day
HDL level
non-HDL
LDL
HDL: M>40 F>50
non-HDL: <130
LDL: <100, >190 scary