intravenous medication principles

Question 1

Vesicants

Answer 1

Vasopressors (dopamine, norepi) anthracyclines (doxrubicin), vinca-alkoloids (vincristine, vinblastine), digoxin, foscarnet, nafcillin, mannitol, mitomycin, and promethazine

Question 2

antidote for extravasation for anthracycline, vincristine,

Answer 2

anthracycline: totect or dimethyl sulfoxide

vincristine: hyaluronidase

Question 3

LATTIN

Answer 3

Drugs have absorption or leaching issues with PVC

Lorazepam
Amiodarone
Tacrolimus
Taxanes*
Insulin
Nitroglycerin

most paclitaxel and taxanes require non-pvc but paclitaxal-albumin can be placed in PVC

Question 4

ACID APE

Answer 4

Saline Diluent only (no dextrose)

Ampicillin
Caspofungin (cancidas)
Infliximab (Remicade)
Daptomycin (cubicin)

Ampicillin/Sul (unysin)
Phenytoin (Dilantin)
Ertapenem (Invanz)

Question 5

Outrages Bakers Avoid Salt

Answer 5

Dextrose Diluent only (no salt)

oxaliplatin
bactrim- SMX/TMP
amphotericin B
synercid- quinupristin/dalfopristin

Question 6

fatal mixing

Answer 6

calcium + ceftriaxone= big no
calcium + phosphate= big no

Question 7

filter drugs

Answer 7

GAL, PLAT

Golimumab (Simponi)
Amiodarone
Lorazepam

Phenytoin
Lipids
Amphotericin B
Taxanes, except docetaxel

Question 8

IV drugs @ room temp
Dear Sweet Pharmacist Freezing Makes Me Edgy!
DSPFMME

Answer 8

• Dexmedetomide (Precedex)
• SMX/TMP (Bactrim)
• Phenytoin- crystalizes
• Furosemide- crystalizes
• metronidazole
• moxifloxacin (Avelox)
• Enoxaparin (Lovenox)

Question 9

light protectant during admin
Protect Every Necessary Med from Daylight
PENMD

Answer 9

-phytonadione (vitamin K, mephyton)
-Epoprostenol (Flolan)
-Nitroprusside (Nitropress)
-Micafungin (Mycamine)
-Doxycycline

Question 10

PS PORCS

Answer 10

Cyp inducers

phenytoin
smoking
phenobarbital
oxcarbazepine
Rifampin
carbamazepine
St. john’s wort

Question 11

G <3 PACMAN

Answer 11

Grapefruit
<3
Protease inhibitors (especially ritonavir)
Azole (antifungals)
Cyclosporine, cobicistat
Macrolides (clarithromycin and erythromycin, not azithromycin)
Amiodarone (& dronedarone)
Non-DHP CCBs (diltiazem & Verapamil)