Week 9- Pyometra Flashcards
Define pyometra.
A hormonally mediated, pus-filled uterus caused by bacterial infection in dioestrus.
Fill in the blank: Pyometra is most commonly caused by ______ infection.
Bacterial (especially E. coli)
True or False: Bacterial contamination of the uterus always results in pyometra.
False
What hormone is primarily responsible for creating conditions favorable to pyometra?
Progesterone
Which age group of bitches is most commonly affected by pyometra?
Middle-aged to older bitches (>6 years)
Name two breeds overrepresented for pyometra.
Bullmastiffs, Golden Retrievers (also Dogue de Bordeaux, CKCS, Rottweilers, etc.)
True or False: Exogenous oestrogen administration reduces the risk of pyometra.
False
What uterine condition often precedes the development of pyometra?
Cystic Endometrial Hyperplasia (CEH)
Fill in the blank: Exogenous ______ administration significantly increases the risk of pyometra.
Oestrogen
List three common clinical signs of pyometra.
Lethargy, PU/PD, vomiting
What is the major clinical difference between open and closed pyometra?
Open has vulval discharge, closed usually does not.
True or False: A bitch with a closed pyometra is more likely to be systemically ill.
True
What is the diagnostic test of choice for confirming pyometra?
Ultrasound
Fill in the blank: A typical haematology finding in pyometra is marked ______ with a left shift.
Neutrophilia
What biochemical finding may indicate endotoxic renal damage?
Increased creatinine and urea
True or False: Proteinuria can occur in pyometra due to glomerulonephropathy.
True
What is the treatment of choice for pyometra in most cases?
Ovariohysterectomy (surgical removal of uterus and ovaries)
List one indication for medical management of pyometra.
Breeding potential to be retained
Name one antiprogestagen used in medical treatment of pyometra.
Aglepristone (Alizin)
True or False: Medical treatment of pyometra is always successful and prevents recurrence.
False
Fill in the blank: Prostaglandins like PGF2-alpha cause ______ and uterine contractions.
Luteolysis
Which drug inhibits prolactin and is sometimes used in pyometra treatment?
Cabergoline
True or False: Vaginal swabs provide a reliable culture result in pyometra cases.
False
What broad-spectrum antibiotic is commonly used in pyometra?
Potentiated amoxicillin or cephalosporin
What is stump pyometra?
Infection of residual uterine tissue post-OVH due to ovarian remnant or exogenous hormones.
What is the most common bacterium isolated in pyometra?
Escherichia coli (E. coli)
True or False: Pyometra can occur in cats and rabbits.
True
