Week 6 RA drugs- Trachte Flashcards
1
Q
Methotrexate
A
Folate metabolism inhibitor
-T and B Cell
2
Q
Hydroxychloroquine
A
INHIBITS MACROPHAGES
(maybe TLR 9) in dendritic
3
Q
Leflunomide
A
Pyrimidine synthesis inhibitor in T-cells
4
Q
Sulfsalazine
A
Inhibits COX and scavenges free radicals
-Antigen presenting cells and T Cells
5
Q
Gold
A
Reduces macrophages phagocytosis and affects antigen presenting cells and T-cells
6
Q
Azathioprine
A
Blocks DNA synthesis, primary site of action T cell
7
Q
Cyclosporine
A
Calcineurin inhibitor to
INHIBIT T-CELL ACTIVATION!
8
Q
Etanercept, Inflixumab
A
BLOCK TNF ALPHA ACTION
9
Q
Anakinra
A
Interleukin 1-receptor antagonist
10
Q
Abatacept
A
blocks t-cell activation by antigen presenting cell
11
Q
Ritixumab
A
BLOCKS B-CELL ACTIVATION
