Week 4 NeuroCommunication- Fitz Flashcards
1
Q
Botulinum Toxin
A
destroy components of the docking apparatus that are required for vesicle fusion in neurons that utilize acetylchoine as a neurotransmitter: PREVENTING MUSCLE CONTRACTION
2
Q
Tricyclin antidepressants, cocain, amphetamine, SSRIs
A
block re-uptake
3
Q
Tetanus toxin
A
- destroys the components of the docking apparatus, selectively in inhibitory neurons.
- Toxin is transported retrogradely back across synapse
- Taken up by synaptic terminals where it blocks release of INHIBITORY neurotransmitters
- Motor neurons become OVERACTIVE
- Spastic paralysis