Week 3 - Lesson 1 (Part 7) Flashcards
What does collateral flow arise from?
Ischemia in the presence of atheromatous disease
- re-routing due to blockages
Ischemia
No oxygen to the tissues which result in cell death
Collateral flow
Circulation to tissue or an organ can be maintained using a different pathway
- occurs over time
Anastomosis
Branches form between adjacent blood vessels
- connection between 2 veins
Where can collateral circulation be established? (2)
- In the venous system
- between veins - In the arterial system
- between arteries
What is an example of collateral flow?
Blood flow to the brain is maintained through a network of collaterals that anastomose in the circle of Willis
What compensatory mechanisms come into play in an attempt to preserve perfusion during atherosclerosis? (3)
- Development of a collateral circulation
- A degree of local dilatation of the affected arterial segment
- An increase in the extraction efficiency of oxygen from blood
What is one factor used to control the flow rate to the organ?
The degree of constriction of distal arterial bed
What happens to flow rate as the resistance to flow of diseased arteries increases?
It is maintained within normal levels as a result of arteriolar dilatation
What are very high degrees of stenosis are accompanied by? (2)
- Low flow rate
- Low velocities
- damped and trickle flow
What are 3 types of flow waves?
- Triphasic
- Biphasic
- Monophasic
What are 2 types of beds?
- Low resistant bed
2. High resistant bed
What is an example of a low bed resistance? (7)
- Brain
- Kidneys
- Liver
- Vertebral arteries
- Distal ICA
- Ovaries
- Testicles
What is an example of a high bed resistance? (3)
- Muscles at rest
- Arms and legs
- peripheral circulation - Small intestines
- not during digestion
Low resistance beds
Structures with metabolic processes that needs continuous forward flow throughout the cardiac cycle
