Week 3 - Lesson 1 (Part 5) Flashcards

1
Q

How is the blood flow to the body tissues and organs normally adjusted?

A

By changes in the degree of vasoconstriction

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2
Q

Where does vasoconstriction occur?

A

In the arterioles according to the tissues needs at a given point in time

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3
Q

What are the arterioles considered in the vascular tree?

A

Stopcocks

- principle point of resistance to blood flow in the circulatory system

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4
Q

Where does blood pressure take the biggest drop?

A

At the stopcock in the arterioles of the vascular tree

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5
Q

Autoregulation

A

Is the ability of most vascular beds to constrict in response to a rise in blood pressure and dilate in response to a fall in blood pressure
- vasoconstriction/vasodilation

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6
Q

What is phenomenon called of autoregulation?

A

Reactive hyperemia

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7
Q

Reactive hyperemia

A

Increase in blood flow which follows restoration of arterial inflow to a previously ischemic limb

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8
Q

What is an example of reactive hyperemia?

A

During exercise induced increased heart rate and vasodilation of arterioles to allow more flow to muscular branches

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9
Q

What happens to the diameter in vasoconstriction?

A

It decreases

- SVR increases

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10
Q

What happens to the diameter in vasodilation?

A

It increases

- SVR decreases

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11
Q

What causes high arterial pressure?

A

High volume of blood in the large and medium sized arteries

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12
Q

How is large volumes preserved?

A

By maintaining a balance between the amount of blood that enters and leaves the arterial tree

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13
Q

What is the amount of blood entering determined by?

A

Cardiac output

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14
Q

What is the amount exiting determined by? (2)

A
  1. Arterial pressure
  2. Total peripheral resistance
  • dependant on status of microcirculation
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15
Q

Cardiac output

A

How well the heart is working

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16
Q

What 3 vessels are involved in microcirculation?

A
  1. Arterioles
  2. Capillaries
  3. Venules
17
Q

What is the driving pressure for flow within a vessel determined by? (2)

A
  1. Potential energy

2. Kinetic energy

18
Q

What is potential energy generated by?

A

The left ventricular contraction that distends the vessel wall

19
Q

What is kinetic energy acquired by?

A

Flow itself

20
Q

Pulsatile arteriel flowsignal

A

Is a summation of forward flow from the left ventricle and reverse flow from the tidal reflection

21
Q

How is energy lost created?

A

Through friction of blood at the vessel walls and between adjacent layers of blood

22
Q

Where is energy loss the highest?

A

In the region of stenosis due to considerable friction during turbulent flow and vortex type motion

23
Q

What happens to blood within a stenosis?

A

An increase in blood kinetic energy associated with the increase in blood velocity
- blood is slower at the walls and faster in the centre

24
Q

What is said according to Bernouilli’s principle?

A

There is a corresponding fall in blood pressure immediately after the stenosis

25
Q

Compliance

A

The ability of a vessel to distend and increase volume with increasing transmural pressure
- the vessel can recoil towards its original dimensions

26
Q

What does the ability of arteries and veins to stretch has a large effect on? (2)

A
  1. Perfusion

2. Blood pressure

27
Q

How much larger is venous compliance compared to arteries?

A

30x

28
Q

What is an increase in arterial stiffness due to?

A

Atheroma

- and is detrimental

29
Q

When does atheroma occur?

A

Over time

- not over night

30
Q

Atheroma

A

Plaque build up

31
Q

What 2 ways can atheroma show up on US?

A
  1. Hyperechoic plaque

2. Hypoechoic plaque

32
Q

Hyperechoic plaque (3)

A
  1. Calcifications
  2. Creates shadows
  3. Can cause embolisms if broken off
33
Q

Hypoechoic plaque

A

Smooth