Vessels of the Lower Limb Flashcards

1
Q

Why is the femoral artery vulnerable to injury/laceration?

A

it is positioned superficially in the femoral triangle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the clinical importance of the femoral artery?

A

it can be easily accessed in most people:

  1. to obtain ABG (arterial blood gas) in emergencies if there is poor peripheral perfusion/pulses
  2. to undertake minimally invasive procedures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the borders of the femoral triangle and the vessels that pass through it?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How is the femoral artery used as an important access point?

A

a catheter can be placed into the femoral artery which can then be advanced up the arterial tree to the target organ

this provides minimally invasive access to perform procedures including:

  1. coronary angiography
  2. coronary angioplasty
  3. embolisation of berry aneurysms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Why might the femoral vein be used in an emergency?

A

it is used for emergency IV access temporarily in:

  1. trauma
  2. burns
  3. otherwise very difficult access - (VDU, thrombosed peripheral veins, obesity)

It can also be used for venepuncture and VBG in emergencies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When is the great saphenous vein used clinically?

Where is it positioned?

A

it lies immediately in front of the medial malleolus

it can be used in emergencies to obtain IV access

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is meant by vascular disease of the lower limb?

A

it is a disease of the lower limb arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is lower limb ischaemia most commonly caused by?

A

atherosclerotic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is meant by ischaemia?

A

when perfusion fails to meet the demands of tissues

tissue hypoxia and anaerobic metabolism result

this leads to tissue damage and death is adequate perfusion is not restored

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the difference between chronic and acute ischaemia?

A

chronic ischaemia:

a gradual process caused by atherosclerosis

acute ischaemia:

a sudden loss of perfusion of the the limb

it is usually the result of an occlusive thrombus or embolus in an artery, but can also occur secondary to trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the disease process behind atherosclerosis?

What happens if the plaque remains stable or ruptures?

A

lipids are deposited in lesions in the walls of large arteries

plaques may remain stable and partially occlude the artery to cause symptoms

if inflammation continues in a plaque, they become unstable and rupture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens when an atherosclerotic plaque ruptures?

A

the contents of the core are exposed to blood

the core is highly thrombogenic

this leads to platelet aggregation and the activation of the coagulation cascade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

After rupture of an atherosclerotic plaque, what 2 types of thrombus may form?

A
  1. a thrombus that stays where it is but occludes the vessel lumen
  2. a thrombus that breaks away from the vessel wall (embolus) and travels downstream to lodge or occlude a smaller vessel

They both lead to an ischaemic event

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where does atherosclerosis tend to happen?

A

It affects large and medium conduit arteries

It occurs due to turbulence of blood flow at bifurcation points

It commonly affects the coronary, carotid and lower limb arteries as well as the aorta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the 4 levels in the Fontaine Classification of limb ischaemia?

A
  1. asymptomatic
  2. intermittent claudication
  3. ischaemic rest pain
  4. ulceration/gangrene (= critical ischaemia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What happens during the early stages of chronic lower limb ischaemia?

A

it is a gradual process so is asymptomatic for some time

the plaques grow and blood flow is increasingly obstructed, but there is time for collateral circulation to develop

at first occlusion is only noticeable when the patient is active

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What happens as chronic lower limb ischaemia develops and the patient becomes more symptomatic?

A

perfusion cannot meet the oxygen demands of the limb muscle, leading to anaerobic metabolism in muscle cells

this is ischaemia and causes pain - intermittent claudication

initially, the pain is relieved with rest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the 2 main signs of critical ischaemia as a result of chronic lower limb ischaemia?

A
  1. pain at rest
  2. ulceration and gangrene

patients may not present until they have ulceration/gangrene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the 3 main signs of critical ischaemia in the foot?

A
  1. foot pain at rest
  2. ulceration
  3. gangrene
21
Q

What is ‘wet’ gangrene?

What does the affected part of the foot look like and what can it lead to?

A

tissue necrosis + infection

affected part is black, soft and putrid

it can rapidly lead to sepsis and death

22
Q

What is ‘dry’ gangrene?

What does the affected area look like?

A

tissue necrosis without infection

the toes are usually affected first and become black, dry and shrunken

23
Q

Which type of gangrene usually occurs in chronic ischaemia and why?

A

dry gangrene

a minimal blood supply means there is limited oxygen and glucose to drive a bacterial infection

24
Q

How should you act when seeing a case of potential acute limb ischaemia?

A

Acute limb ischaemia is a surgical emergency

Rapid recognition and action is required if the limb is to be saved

If the ischaemic limb is not revascularised within a matter of hours, it cannot be preserved

25
Q

What is the most common cause of acute (sudden) limb ischaemia?

A

rupture of an atherosclerotic plaque

this results in complete occlusion of the artery by a thrombus iin situ

or an embolus that travels down the arterial tree until it becomes stuck in a smaller vessel and occludes it

26
Q

What are the other 2 common causes of acute limb ischaemia?

A
  1. emboli from elsewhere (e.g. heart in patient with AF)
  2. patients who have undergone recent angioplasty or grafting of an occlusion may also present with acute limb ischaemia
27
Q

What are the 3 things to look out for and consider in acute limb ischaemia?

A
  1. tissue perfusion suddenly ceases
  2. the patient does not have a collateral circulation to maintain tissue perfusion
  3. there is usually a clear history and the leg is markedly abnormal when compared to the unaffected leg
28
Q

What are the 6 P’s of acute limb ischaemia?

A

Polar (cold)

Pallor

Pain

Pulseless

Paralysis

Paresthesias (tingling, chilling, etc.)

29
Q

What is meant by ‘intermittent claudication’?

A

a cramping leg pain that develops when walking and is relieved with rest

the pain occurs on activity as a result of impaired limb perfusion

30
Q

What investigations are carried out following an acute ischaemic limb?

A

investigations into the cause are carried out

this includes blood tests (inflammatory markers), ECG, Echo, etc.

Vascular disease elsewhere in the body should also be searched for and treated (e.g. coronary arteries, carotid doppler)

31
Q

What is involved in the management of an acute ischaemic limb?

A
  1. initiating/optimising the treatment of risk factors - e.g. diabetes, hypertension, hyperlipidaemia
  2. lifestyle modification and eduction - e.g. diet, smoking cessation
32
Q

What causes varicose veins?

A

increased pressure in the saphenous veins can be caused by proximal venous obstruction

e.g. pregnancy or venous tumour

this leads to the veins becoming dilated and incompetent

33
Q

What is a consequence of the saphenous veins becoming dilated and incompetent in varicose veins?

A

blood may stagnate in the skin

this leads to breakdown and ulceration

34
Q

What are the 3 main complications associated with varicose veins?

A
  1. bleeding
  2. superficial thrombophelbitis
  3. venous/varicose ulcers on the medial side of the ankle, dermatitis and skin thickening
35
Q

What is superficial thrombophlebitis?

A

inflammation of a vein caused by a blood clot just below the surface of the skin

36
Q

What is a deep vein thrombosis?

What does the leg look like in DVT?

A

it is a thrombus in the deep veins of the pelvis or legs

the limb appears swollen, red, warm and painful

it is tender on examination

37
Q

What is the main risk associated with DVT?

A

clots can break off from the vein wall and travel to the lungs

this is a pulmonary embolus

38
Q

What is the mortality risk associated with untreated DVT?

What questions should always be asked?

A

1-2% mortality risk from pulmonary embolism

you should always ask about chest pain and shortness of breath

39
Q

What types of long term symptoms are associated with DVT?

A

50% of patients with DVT will have long-term pain and swelling in the affected leg

40
Q

What are the major risk factors for DVT (8)?

A
  1. previous VTE
  2. immobility
  3. recent lower limb surgery
  4. recent lower limb fracture
  5. malignancy
  6. pregnancy
  7. IV drug use (injecting into femoral vein)
  8. sepsis
41
Q

What are the 3 stages involved in management of DVT?

A
  1. calculate Well’s score
  2. give anticoagulants
  3. US scan of the LL veins
42
Q

What are the main modifiable risk factors that accelerate atherosclerotic disease?

A
  1. smoking
  2. diabetes
  3. hypertension
  4. hyperlipidaemia
43
Q

What is vascular interventional radiology?

A

the use of imaging techniques to effect treatment, rather than just diagnosis

it is a minimally invasive alternative to surgery

44
Q

What is ABPI?

A

ankle brachial pressure index

it is a calculation of the ratio of the patient’s systolic blood pressure at their ankle to the systolic pressure in their arm

45
Q

What is normal ABPI?

A

1.0 - 1.2

46
Q

What does an ABPI > 1.2 suggest?

A

the vessel is abnormally hard (e.g. calcified)

there is likely significant peripheral vascular disease

47
Q

What does an ABPI <0.5 suggest?

A

Severe arterial disease: rest pain, ulceration and gangrene (critical ischaemia)

48
Q

What happens to vessels when there is a stenosis or blockage?

How does this affect intermittent claudication?

A

collateral arteries develop to bypass the blockage

intermittent claudication allows you to walk as the muscle is still receiving blood, but there is pain as the blood takes longer to reach the muscle through the collateral vessels

49
Q
A