vaccines Flashcards

1
Q

Killed vaccines-bacterin

A
antigenically intact
can't replicate
unable to induce disease
Requires adjuvant
inactivated-chemicals
often need multiple doses
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2
Q

does modified live require adjuvant

A

no, it’s growing and dividing so doesn’t need it

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3
Q

Subunit vaccines- toxoid

A

does not contain entire intact organism
specific immunogenic structural antigens
requires adjuvant

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4
Q

marker vaccines

A

discriminates between vaccine and exposure titers
differentiating infected from vaccinated animals
needs appropriate diagnostic test

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5
Q

what are some manufacturing errors

A

immunosuppression
clinical disease
death
abortion

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6
Q

how might a vaccine not work

A
prior passive immunizationh
immunosuppressed
inadequate vaccine
wrong organism
given too late
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7
Q

Common incorrect administration

A

death of live vaccine

inappropriate route

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8
Q

vaccine reactions

A

hypersensitivity
neuro
foreign body reaction

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9
Q

heterologous vaccine

A

antigenically related to target agent
no adjuvant required
adapted to different host species

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