mucus Flashcards
Where are activated effector cells
Lamina propria and epithelium
Where are naive lymphocytes located
organized follicles
What does MALT stand for
Mucosal associated lymphoid tissues
Where is GALT
salivary glands, tonsils, Peyer’s patches, lymph nodules
What does GALT do
site of Ag processing and initiation of the mucosal immune response
What are M-cells
Specialized APC over the dome of Peyer’s patches in the gut
What do M-cells interact with
have intimate interaction with dendritic cells
Where are convential CD8 T cells found
Lamina propria
Where are nonconventional CD8 T cells found
Intraepithelial lymph
What are the two populations of memory/effector T cells
Conventional and nonconventinal
What are some characteristics of conventional CD8 T cells
Alpha/beta, MHC 1 restricted
Cytotoxic
What is the major characteristic of nonconventianal CD8 T cells
non MHC restricted
What Ig is unique to mucosal immunity
IgA
What is Dimeric IgA transformed into and when
SIgA as it is transported from the submucosa, through the epithelial cells
What does sIgA do
prevention of bacterial and viral adherence to mucosal surfaces
Do not activate complement
Do not initiate inflamation
