transplatation immunology Flashcards
isograph
twins
allograft
same species
xenograft
different species
transplant rejection
determined by co-dominant genes
offspring accepts parents
parents don’t accept offspring
autograph
graft to itself
acute cellular rejection
t cells
chronic rejection
persistent antibodies produced
fibrosis
hyper acute rejection
hypersensitivity type 2
acute rejection
hypersensitivity type 4
chronic rejection
hypersensitivity type 3/4
prevention and treatment of allograft rejection
reduction of immunogenicity
-elimination of leukocytes
-minimize alloantigenic differences
suppression
major cross matching
are there ab in the recipient serum that will recognized the RBCs of the donor
Minor cross match
are there Ab in the donor serum that will recognize the recipient’s RBCs
Transfusion reactions
recipient antibodies to blood group antigen
bone marrow transplant
irradiate