Exam questions-Milner Flashcards
1
Q
T/F: macrophages play no role in the body’s immune response to cancer
A
False
2
Q
T/F: With MHC restricted tumor antigen presentation, lack of inflammation and lack of costimulatory molecule expression can lead to tolerance
A
True
3
Q
Killing of cancer cells in the body by NK-cells is thought to be primarily mediated by
A
CD95/CD95 ligand receptor interactions
4
Q
What are some reasons for failure of the immune response in cancer patients
A
Development of tolerance
Down regulation of MHC-1 receptors on cancers
Suppressor cells
Blocking antibodies