Exam questions- Terrell Flashcards
What are cytokines primary role
Influence inflammation and immune response
What cytokine down-regulates the immune response by inhibiting activation of macrophages
IL-10
Which cytokine is dependent on the amount of cytokine present in circulation
TNF-a
Pleiotropy
Cytokines act on multiple cell types inducing different responses
Erythropoietin is produced by what cell type
renal fibroblasts
What are complications reported in association with erythropoietin therapy treatment
Development of: Polycythemia, antibodies to recobminate EPO, auto-antibodies against endogenous EPO
IL-5 anti-parasite reactions effect what cell type
eosinophiles
O2 is produced through which enzyme
NADPH oxidase
Where in the cell is NADPH oxidase found
lysosome membrane
what cell types are the most important effector cells in ADCC
NK cells and eosinophils
what cell type requires functional MHC type 1 to recognize and destroy virus infected cells
cytotoxic T lymph
leukocyte adhesion deficiency is a disorder of cell mediated immunity caused by a lack of
integrin, ability of neutrophils to infiltrate tissues
what does feline leukiemia virus and feline immunodeficiency virus cause
immunosuppression due to effects on CD4 t lymph
what is the basic parthenogenesis of immunosuppression due to parvo virus infection
destruction of rapidly dividing cells and decrease in bone marrow and lymphoid fucntion
What is the basic parthenogenesis of immune dysfunction in CID Arabian foals
Hypoplasia of both T and B cell tissues and lack of lymph mediated immunity
