passive immunity Flashcards
neonatal responses
30 days-12 months for full competency
neutrophils and macrophage functions deficient
low B cells
IL-10 (immunosuppressant) more active
what animals have no placental transfer of AB
horses and cows
What is colostrum
first udderfull of milk full of antibodies
IgG
derived from serum
passive immunity
immunity to recipient from an immune donor
humoral factors
temporary acquisition
no active response
what effect on neonatal IgG does colostral IgG have
down regulatory
lots of antibody come in, negative feedback loop activated stoping antibody production
What happens in failure of passive transfer
inverse relation between passive transfer of immunity and mortality
adequate amounts of Ig transfer may still not mean production
failure of timely ingestion