UWORLD random 3/19b Flashcards

1
Q

ectopic pregnancy uterine biopsy

A

decidualized endometriumm

dilated coiled endometrial glands
vascularized endematous stroma
(luteal phase)

NO embryonic and trophoblastic tissue

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2
Q

heterochromatin

A

inactive

Barr body

heavily methylated DNA

deacetylated histones

low transcriptional activity

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3
Q

antitoxin

A

passive immunization

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4
Q

pelvic fracture + inability to void despite full bladder sensation

A

urethral injury

foley catheter is contraindicated

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5
Q

statistical power

A

1-B

study’s ability to detect a difference when 1 exists

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6
Q

blue-violet or brownish dermal plaques on feed/legs and spread proximally

A

kaposi’s sarcoma

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7
Q

l ovarian vein drains into…

A

l renal vein

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8
Q

r ovarian vein drains into…

A

IVC

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9
Q

succinylcholine NMJ blocker

A

depolarizing agent

phase I = prevent repolarization of motor endplate

phase II = desensitize and inactivate ACh receptors

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10
Q

digeorge/velocardiofacial

A

chr 22q11.2 deletion

defective development of pharyngeal pouches 3-4

cardiac
abnormal facies
thymic hypoplasia/aplasia (t-cell def)
craniofacial (cleft)
hypocalc/hypopth

dx FISH

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11
Q

tetrology of fallot

A

cyanotic spells better with squatting
systolic murmur

cyanosis due to R–>L shunt with RVOT obstruction (infundibular septum deviation)

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12
Q

duchenne muscular dystrophy

A

gower sign
muscle weakness
calf pesudohypertrophy
elevated CK

x-linked

early stop codon
UAA
UAG
UGA

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13
Q

SLE antismith antibodies

A

anti snRNPs

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14
Q

CD4 & CD8 antigens

A

immature cortical t lymphocytes in thymus

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15
Q

dopamine dosing

A

vary effects based on dose

low = D1 = renal vasculature (+ blood flow)

med = B1 = heart (chronotropic)

high = a1 = vasculature (vasoconstriction)

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16
Q

dilated pupils, yawning, lacrimating, hyperactive bowel sounds, NV, ab cramps, muscle aches

A

heroin withdrawal

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17
Q

zolpidem

A

short acting hypnotic

unrelated to benzos but act similarly (GABA-A agonist)

short term tx insomnia, less addiction

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18
Q

class 4 antiarrhythmics

A

block Ca channels in nodes

reduce HR

slow phase 4 diastolic depol

19
Q

TPR for vessels in parallel

A

1/TPR = 1/R1 + 1/R2… etc

20
Q

restrictive lung disease due to obesity lung fxn tests

A
  • FEV1
  • FVC*
  • ERV*
  • TLC

normal RV

21
Q

circular nonnuclear DNA

A

mitochondrial DNA

22
Q

jugular foramen

A

CN 9,10,11, jugular vein

23
Q

cribriform plate

A

CN 1

24
Q

optic canal

A

CN 2
ophthalmic artery
central retinal vein

25
Q

sup orbital fissure

A

CN 3, 4, 5-1, 6
ophthalmic vein
sympa fibers

26
Q

foramen rotundum

A

CN 5-2

27
Q

Foramen ovale

A

CN 5-3

28
Q

foramen spinosum

A

middle meningeal artery and vein

29
Q

internal acoustic meatus

A

CN 7, 8

30
Q

hypoglossal canal

A

CN 12

31
Q

foramen magnum

A

spinal roots of CN 11, brain stem, vertebral arteries

32
Q

cystinuria

A

COLA

+ risk kidney stones

low urine pH

33
Q

photoaging

A

UVA wavelengths

increased collagen crosslinking

thinning of epidermis

decreased collagen fibril production

34
Q

perianal fistula

A

Crohn’s disease

35
Q

HUS from e coli serum levels

A

+ serum indirect bilirubin

due to hemolytic anemia

36
Q

hyperkalemia drugs

A
nonselective BB
ACEi
ARBs
k-sparing diuretics
cardiac glycosides (digoxin)
NSAIDs
37
Q

ADHD dx

A

inattention or hyperactivity in at least 2 settings

38
Q

tx genital herpes

A

-cyclovir

nucleoside analog –> terminate nucleic acid synthesis

39
Q

HIV retinitis

A

CMV

tx gancyclovir

40
Q

gram pos cocci in chains with UTI

A

enterococcus

gamma hemolysis

41
Q

Hib vaccine

A

paired with tetanus antitoxoid = T-cell mediated response

polysaccharide capsule = B cell immune response

42
Q

CREST syndrome

A
calcinosis
raynaud's
esophgeal dysmotility
sclerodacyly
telangiectasia

anti-centrometere

43
Q

diffuse scleroderma

A

diffuse skin and visceral involvement

anti-DNA topo I
Scl-70

44
Q

juvenile hemangioma

A

cutaneous
strawberry-type
capillary

benign, common

initially grow proportional to child and regress spontaneously at/before puberty