SECRETS GI - Basics Flashcards
major stimulus for gastrin release & from where
protein in stomach
also stomach distention, alkalinization, & vagal stimulation
from G cells in antrum
gastrin stimulates…
HCl & IF release from parietal cells
pepsinogen release from chief cells
inhibitor of gastin release
decreased gastric pH –> somatostatin release
___ secretes somatostatin
D cells in pancreas and GI mucosa
pancreatic enzymes
trypsin, chymotrypsin = proteins amylase = carbs lipase = triglycerides DNase and RNase enzymes bicarbonate
cholecystokinin
stimulates secretion of enzymes from pancreatic acinar cells
stimulates gallbladder contraction, relaxation of sphincter of Oddi –> bile entry
delays gastric emptying
in response to fatty acids in duodenum
from duodenum
secretin
stimulates secretion of bicarb rich fluid from pancreatic ductal cells
in response to adicification of duodenum
from duodenum
bile salts
solubilize fats
form micelles
formed from degradation of cholesterol in liver via 7a-hydroxylase
foregut + blood/nerve supply
upper GI to ampulla of Vater (1st part of duodenum)
celiac artery
vagus nerve
includes pancreas, liver, spleen
midgut + blood/nerve supply
2nd part of duodenum to splenic flexure of colon
superior mesenteric artery
vagus nerve
hindgut + blood/nerve supply
splenic flexure to anus
inferior mesenteric artery
pelvic nerve
anatomic layers of gut wall
mucosa
submucosa
muscularis propria
serosa
location of meissner’s plexus
in submucosa
location of myenteric (auerbach’s plexus)
muscularis propria
between circular & longitudinal muscle layers
taeniae coli
band-like muscles of outer longitudinal smooth muscle layer of large intestine
