Urinary Tract Flashcards
Nephron
Functional unit of kidney that is responsible for the resorption of water and filtration of blood
Renal corpuscle
Glomerulus (visceral) and Bowmen’s capsule (parietal) filters blood
Proximal tubule
Convoluted tubule adjacent to the renal corpuscle. Prominent microvilli brush border. Absorbs most of the water from the filtrate. Surrounded by vasculature.
Loop of Henle
thick descending, thin descending (shorter), thin ascending (longer) and thick ascending duct
Distal tubule
Thick ascending duct and thick convoluted tubule. Contains abundant mitochondria. NO absorption in the ascending
Macula densa
Region of specialized cells in the distal convoluted tubule that controls flow of blood into renal corpuscle by stimulating adjacent juxtaglomerular cells to release renin
Glomerulus
Corpuscle that contains highly branches arterioles and
capillaries that form the filtrate.
Renin
Secreted by juxtaglomerular cells. Causes an increase in blood flow and pressure within the glomerulus. Gives feedback for filtration to the new cells that are entering the tubules.
Podocytes
Cell bodies within the glomerulus that have epithelial cytoplasm branches that surround capillaries and form filtration slits to facilitate the filtration of blood
Pedicels
Foot processes that surround the terminal ends of the capillaries, area where blood squeezes through from the capillaries into the urinary space.
Mesangial cells
Clean up the basement membrane of debris from around the capillaries
Filtration membrane
Consist of a fenestrated capillary membrane, thick basement membrane, and a filtration slit diaphragm between pedicles.
Filtrate
Water, glucose, amino acids, ions, urea, hormones, vitamins, and very small amounts of proteins
Aldosterone
promotes Na+ and water reabsorption in the distal convoluted tubules and collecting ducts.
Vasopressin (ADH)
increases permeability of collecting ducts to water which is osmotically pulled from the filtrate.