Urinary Tract Flashcards

1
Q

Nephron

A

Functional unit of kidney that is responsible for the resorption of water and filtration of blood

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2
Q

Renal corpuscle

A

Glomerulus (visceral) and Bowmen’s capsule (parietal) filters blood

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3
Q

Proximal tubule

A

Convoluted tubule adjacent to the renal corpuscle. Prominent microvilli brush border. Absorbs most of the water from the filtrate. Surrounded by vasculature.

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4
Q

Loop of Henle

A

thick descending, thin descending (shorter), thin ascending (longer) and thick ascending duct

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5
Q

Distal tubule

A

Thick ascending duct and thick convoluted tubule. Contains abundant mitochondria. NO absorption in the ascending

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6
Q

Macula densa

A

Region of specialized cells in the distal convoluted tubule that controls flow of blood into renal corpuscle by stimulating adjacent juxtaglomerular cells to release renin

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7
Q

Glomerulus

A

Corpuscle that contains highly branches arterioles and

capillaries that form the filtrate.

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8
Q

Renin

A

Secreted by juxtaglomerular cells. Causes an increase in blood flow and pressure within the glomerulus. Gives feedback for filtration to the new cells that are entering the tubules.

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9
Q

Podocytes

A

Cell bodies within the glomerulus that have epithelial cytoplasm branches that surround capillaries and form filtration slits to facilitate the filtration of blood

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10
Q

Pedicels

A

Foot processes that surround the terminal ends of the capillaries, area where blood squeezes through from the capillaries into the urinary space.

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11
Q

Mesangial cells

A

Clean up the basement membrane of debris from around the capillaries

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12
Q

Filtration membrane

A

Consist of a fenestrated capillary membrane, thick basement membrane, and a filtration slit diaphragm between pedicles.

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13
Q

Filtrate

A

Water, glucose, amino acids, ions, urea, hormones, vitamins, and very small amounts of proteins

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14
Q

Aldosterone

A

promotes Na+ and water reabsorption in the distal convoluted tubules and collecting ducts.

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15
Q

Vasopressin (ADH)

A

increases permeability of collecting ducts to water which is osmotically pulled from the filtrate.

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16
Q

Vasa recta

A

Extensive vasculature surrounding the loop of Henle. Important for reabsorbing most of the water and some of the Na ions

17
Q

Cortex

A

Contains the corpuscles

18
Q

Medulla

A

Contains the tubules

19
Q

Layers of the medulla

A

Outer stripe -> Inner stripe -> Inner zone

20
Q

Outer stripe

A

Thick descending and thick ascending tubule. Collecting duct

21
Q

Inner stripe

A

Thick ascending and thin segment. Collecting duct

22
Q

Inner zone

A

Thin segments. Collecting duct

23
Q

Collecting duct

A

Resorb water in response to vasopressin. Prominent intercellular borders. Scant mitochondria.

24
Q

Renal papilla

A

Filtrate converges here and empties into calyces which drains into the ureter.

25
Q

Ureter

A

Transitional epithelium surrounded by smooth muscle. Contains binucleated cells