Liver

Question 1

Sinusoids

Answer 1

Vessels of the liver w/ fenestrated epithelium. Both arterial and portal blood mix in the sinusoids as they flow towards the central vein.

Question 2

Lobule

Answer 2

Contains 5 portal traids at the corners and a central vein

Question 3

Portal triad

Answer 3

hepatic arteriole, portal venule, bile duct, and lymphatic vessel. Require limited amounts of connective tissue for support

Question 4

Hering’s canal

Answer 4

Another name for the bile duct. Bile flows out of the liver

Question 5

Space of disse

Answer 5

space between the sinusoid and hepatocyte

Question 6

Hepatocyte function

Answer 6

Protein synthesis, metabolism, bile secretion, and detoxification

Question 7

Kupffer cells

Answer 7

derived from monocytes. Phagocytic cells within the sinusoids

Question 8

Ito cells

Answer 8

Also called hepatic stellate cells and lipocytes. They are fat storing cells in the space of disse and contain abundant lipid droplets. Under diseased conditions, can secrete type I collagen that leads to cirrhosis of the liver

Question 9

Bile canaliculi

Answer 9

Carries the bile from around the central vein to the binary ductule. Formed when 2 adjacent hepatocytes join through tight junctions

Question 10

India ink

Answer 10

Used to identify phagocytic cells

Question 11

Hepatocyte microvilli

Answer 11

Face the space of disse and increase the surface area for absorption

Question 12

Hepatocyte

Answer 12

Liver cells that store glycogen, perform gluconeogenesis, and detoxify toxins

Question 13

Somatomedins (IGFs)

Answer 13

Proteins produced predominantly in the liver that stimulate bone and muscle growth

Question 14

Centrolobular cells

Answer 14

closer to central vein, more glycolysis and fatty acid synthesizing enzymes

Question 15

Perilobular cells

Answer 15

Higher oxygen concentration and extra hepatic hormones. More glucose liberating and fatty acid oxidation enzymes