Male Reproduction Flashcards

1
Q

Gubernaculum testis

A

connective tissue extending from testis to what will become scrotum

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2
Q

Pampiniform plexus

A

Countercurrent heat exchange system that cools abdominal blood passing to testis and epididymis, heats blood returning from testis and epididymis to abdomen

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3
Q

Mesonephric tubules

A

Becomes the efferent ducts

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4
Q

Mesonephric ducts

A

Becomes the epididymus and vas deferens

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5
Q

Layers of the testes

A

Visceral tunica vaginalis –> tunica albuginea –> tunica vasculosa

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6
Q

Tunica albuginea

A

Thick connective tissue layer of testis. Contains the septa and mediastinum

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7
Q

Septa

A

Separate the seminiferous tubules

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8
Q

Mediastinum testis

A

posterior portion of the tunica albuginea that forms cavities that the seminiferous tubules empty sperm into

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9
Q

Efferent ducts

A

connects the tunica albuginea to the epididymus. Lined by ciliated and resorptive cells to help sperm move along and to reabsorb fluid

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10
Q

Tunica vasculosa

A

layer of connective tissue with blood vessels that provides nutrients to the seminiferous tubules

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11
Q

Leydig cells

A

Synthesize testosterone in their smooth ER and reside between the seminiferous tubules

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12
Q

Seminiferous tubules

A

Contain Sertoli cells, germ cells, and an outer layer of smooth muscle

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13
Q

LH

A

Stimulates leydig cells

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14
Q

FSH

A

Stimulates Sertoli cells

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15
Q

Inhibin

A

feedback hormone for LH and FSH secreted by Sertoli cells

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16
Q

Sertoli cells

A

Support cells in the seminiferous tubules. Secrete inhibin. Prominent nucleolus. Infolding nuclear membrane

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17
Q

Testosterone

A

Maintain spermatogenesis, maintain accessory glands of reproduction, secondary sex characteristics, and libido

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18
Q

Androgen receptor

A

Binds testosterone

19
Q

Cholesterol

A

Precursor to testosterone

20
Q

Sections of the seminiferous tubules

A

Transitional region (terminal segment) that contains only sertoli cells, tubulus rectus (simple cuboidal), and rete testis

21
Q

Development of sperm cells

A

Spermatogonium -> primary spermatocyte -> secondary spermatocytes -> early spermatids -> sperm

22
Q

Sertoli tight junction complexes

A

It contains a blood testis barrier that separates the basal compartment from the adluminal compartment. The sertoli cells have a role in sustaining the mitotic stem cells because of the separation from the nutrients of the basal compartment.

23
Q

Basal compartment

A

Below the blood testis barrier and contains vasculature. Spermantogium are located here

24
Q

Adluminal compartment

A

Above the blood testis barrier and contains the sperm stem cells. No vasculature

25
Spermatogenesis
The mitotic differentiation of spermatogonia to sperm
26
Spermiogenesis
The process of a round sperm to an elongated sperm
27
Section of sperm
Head --> neck--> middle piece --> principal piece --> end piece
28
Head
acrosome on outer layer, DNA inside
29
Neck
contains the centrioles
30
Middle piece
contains the axoneme. It is wrapped with mitochondria and this provides the energy for motility
31
Principal piece
the axoneme is wrapped in a fibrous sheath
32
End piece
Axoneme only
33
Sequential temporal succession
The same cell types of germ cells differentiate in clusters during spermatogenesis. When the cells are differentiating, there is a communicating within each of them so they can differentiate together
34
Rete testis
spaces within the mediastinum that collects the sperm from the various tubules, ciliated cuboidal
35
Epididymus
Pseudostratified columnar, lined with stereocilia. Empties into the vas deferens
36
Sperm maturation
The ability of sperm to fertilize ova increases during transit through the epididymis
37
Sperm storage
The wide lumen of the tail (cauda) increases storage volume
38
Layers of vas deferens
Inner and outer layers of longitudinal smooth muscle. and middle layer of circular smooth muscle for contraction. Epithelium is folded on the inside (ampulla)
39
Seminal vesicle
One tube, highly folded. Secretes fluid during ejaculation. Pseudostratified columnar or simple columnar.
40
Zones of the prostate gland
Periurethral and central zone (more smooth muscle) and transitional zone
41
Corpora amylacea
Concretions in the prostate that accumulate with age
42
Bulbourethral (Cowper’s) glands
secrete mucin that protects the lining of the urethral from acrosomal proteases and protects sperm from remnants of urine. Contains skeletal muscle
43
Layers of the urethra
Going down the urethra: Prostatic (transitional) --> membranous and penile (pseudostratified and/or Stratified columnar)