Unit 6: Drugs Affecting Smooth Muscle Flashcards
1
Q
Name the Autocoid Drug Groupings
A
Histamines Seratonin Prostaglandins Leukotrienes Cytokines
2
Q
Are the autocoids systemic or local?
A
Local
3
Q
What is the primary use for ergot alkaloids?
A
Migraine treatment
4
Q
What drug class is diphenhydramine, and what is it used for?
A
H1 blocker
Itching, allergies
Sedating
5
Q
What is hydroxizine, and what is it used for?
A
H1 blocker
Itching and anxiety
6
Q
Name the 2nd generation H1 blockers
A
Cetirizine
Fexofenadine
Loratadine
7
Q
Name a major difference between 1st and 2nd generation H1 blockers
A
Sedating vs nonsedating
8
Q
The H2 blockers primarily affect what? What else can they affect?
A
Gastric mucosa
Cardiac muscle, mast cells, brain
9
Q
Name some H2 blockers
A
Famotidine
Ranitidine
10
Q
Name some eicosanoids associated with inflammation, edema, and leukocyte infiltration.
A
PGE2
PGI1
