Unit 1: Pharmacogenomics Flashcards
1
Q
Precision medicine
A
Genetic information used to guide drug and dosing selection
2
Q
Pharmacogenomics
A
Study of genetic factors that might explain variations in responses
3
Q
What is CPIC?
A
Clinical Pharmacogenetics Implementation Consortium
4
Q
PM
A
Poor metabolizer
5
Q
IM
A
Intermediate metabolizer
6
Q
EM
A
Extensive metabolizer
7
Q
UM
A
Ultra rapid metabolizer
8
Q
What happens when phase 2 enzymes are less effective?
A
Drug elimination is delayed, and the person is at higher risk for toxicity
9
Q
Epigenomics
A
Study of inheritable patterns in DNA
