Unit 4 Integumentary Flashcards

1
Q

function

A
  1. mechanical protection
  2. protection from fluid loss
  3. physical barrier
  4. thermoregulation
  5. receptor organ
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2
Q

structure

A
  1. epidermis
  2. dermis
  3. hypodermis (not truly skin)
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3
Q

epidermis

A

a) from surface ectoderm

b) stratified squamous keratinized epithelium

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4
Q

dermis

A

a) mostly from mesoderm

b) dense irregular connective tissue

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5
Q

hypodermis

A

a) loose connective tissue

b) forms superficial fascia

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6
Q

epidermis types

A
  1. thick (glabrous; smooth, nonhairy)

2. thin (hairy)

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7
Q

epidermis layers

A
  1. stratum basale
  2. stratum spinous
  3. stratum granulosum
  4. stratum lucidum
  5. stratum corneum
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8
Q

stratum basale

A

a) one layer thick
b) rests on basal lamina
c) highly mitotic
d) cuboidal to columnar cells

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9
Q

stratum spinous

A

a) cuboidal cells
b) extensive desmosomes – “prickle cells”
c) tonofilaments – keratin

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10
Q

stratum granulosum

A

a) keratohyalin granules – protein; no membrane
b) lamellar bodies – lipid; membrane-bound
(1) sealant effect; water proofing
(2) cells above die

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11
Q

stratum lucidum

A

only in thick skin

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12
Q

stratum corneum

A

a) dead cells
b) no organelles
c) high molecular weight keratin tonofilaments

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13
Q

cells

A
  1. keratinocytes
  2. langerhan’s cells
  3. melanocytes
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14
Q

keratinocytes

A

predominant cell type

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15
Q

langerhan’s cells

A
  1. originate in bone marrow

2. antigen presenting cells

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16
Q

melanocytes

A

a) from neural crest
b) make melanin
c) transfer melanin to cells of stratum basale and stratum spinosum

17
Q

epidermis pigmentation

A
  1. blood
  2. carotene
  3. melanin
18
Q

dermis structure

A
  1. dense irregular connective tissue
  2. variable thickness
  3. fibers – type I collagen and elastic; provide strength and elasticity
  4. cells – fibroblasts and macrophages
  5. ground substance rich in hyaluronic acid, dermatin sulfate and chondroitin
    sulfate
19
Q

dermis layers

A
  1. papillary dermis

2. reticular dermis

20
Q

dermis blood supply

A
  1. arterial plexuses and venous plexuses between papillary and reticular dermis and between reticular dermis and hypodermis
  2. arteriovenous shunts can bypass superficial capillaries to conserve heat and increase blood pressure
21
Q

nerve endings

A
  1. encapsulated

2. free

22
Q

encapsulated nerve endings

A

a) Meissner’s corpuscles

b) Pacinian corpuscles

23
Q

Meissner’s corpuscles

A

in papillary dermis; touch

24
Q

Pacinian corpuscles

A

deep dermis and hypodermis; deep pressure and vibration

25
Q

free nerve endings

A

a) fine touch; temperature

b) abundant around hair follicles

26
Q

eccrine sweat glands

A
  1. wide distribution
  2. simple, coiled tubular glands
  3. secretory cells – simple cuboidal
  4. duct – stratified cuboidal
  5. merocrine secretion
27
Q

hair

A
  1. in thin skin
  2. hair follicle – epidermal origin
  3. sebacous gland
  4. arrestor pili muscle
28
Q

sebaceous gland

A

a) outgrowth of hair follicle
b) secretes sebum into follicle
c) holocrine secretion

29
Q

arrestor pili muscle

A

a) smooth muscle innervated by sympathetic division of ANS

b) contraction causes hair to stand up