Unit 4 Integumentary Flashcards
function
- mechanical protection
- protection from fluid loss
- physical barrier
- thermoregulation
- receptor organ
structure
- epidermis
- dermis
- hypodermis (not truly skin)
epidermis
a) from surface ectoderm
b) stratified squamous keratinized epithelium
dermis
a) mostly from mesoderm
b) dense irregular connective tissue
hypodermis
a) loose connective tissue
b) forms superficial fascia
epidermis types
- thick (glabrous; smooth, nonhairy)
2. thin (hairy)
epidermis layers
- stratum basale
- stratum spinous
- stratum granulosum
- stratum lucidum
- stratum corneum
stratum basale
a) one layer thick
b) rests on basal lamina
c) highly mitotic
d) cuboidal to columnar cells
stratum spinous
a) cuboidal cells
b) extensive desmosomes – “prickle cells”
c) tonofilaments – keratin
stratum granulosum
a) keratohyalin granules – protein; no membrane
b) lamellar bodies – lipid; membrane-bound
(1) sealant effect; water proofing
(2) cells above die
stratum lucidum
only in thick skin
stratum corneum
a) dead cells
b) no organelles
c) high molecular weight keratin tonofilaments
cells
- keratinocytes
- langerhan’s cells
- melanocytes
keratinocytes
predominant cell type
langerhan’s cells
- originate in bone marrow
2. antigen presenting cells
melanocytes
a) from neural crest
b) make melanin
c) transfer melanin to cells of stratum basale and stratum spinosum
epidermis pigmentation
- blood
- carotene
- melanin
dermis structure
- dense irregular connective tissue
- variable thickness
- fibers – type I collagen and elastic; provide strength and elasticity
- cells – fibroblasts and macrophages
- ground substance rich in hyaluronic acid, dermatin sulfate and chondroitin
sulfate
dermis layers
- papillary dermis
2. reticular dermis
dermis blood supply
- arterial plexuses and venous plexuses between papillary and reticular dermis and between reticular dermis and hypodermis
- arteriovenous shunts can bypass superficial capillaries to conserve heat and increase blood pressure
nerve endings
- encapsulated
2. free
encapsulated nerve endings
a) Meissner’s corpuscles
b) Pacinian corpuscles
Meissner’s corpuscles
in papillary dermis; touch
Pacinian corpuscles
deep dermis and hypodermis; deep pressure and vibration
free nerve endings
a) fine touch; temperature
b) abundant around hair follicles
eccrine sweat glands
- wide distribution
- simple, coiled tubular glands
- secretory cells – simple cuboidal
- duct – stratified cuboidal
- merocrine secretion
hair
- in thin skin
- hair follicle – epidermal origin
- sebacous gland
- arrestor pili muscle
sebaceous gland
a) outgrowth of hair follicle
b) secretes sebum into follicle
c) holocrine secretion
arrestor pili muscle
a) smooth muscle innervated by sympathetic division of ANS
b) contraction causes hair to stand up