Unit 2 CT Flashcards
Connective Tissue
connective tissue
most abundant, widely disturbed of primary tissues
4 classes of CT
connective tissue proper
cartilage
bone
blood
CT functions
binding/support (storm of organs) protecting (phagocytosis, immune) insulating storing reserve fuel transport substances
origin
mesenchyme; mostly mesoderm, some ectoderm; pluripotent, lack fibers in ECM
mesenchyme
embryonic precursor of CT
mucoid
mostly extra-embryonic
umbilical cord
fixed cells
produced locally remain in tissue to carry out function
mesenchymal cells
fixed; pluripotent
cytoplasmic extensions
no fibers produced
respond to signals from surrounding matrix/cells & commit to final state
fibroblasts
fixed cells
most common CT
synthesizes type I collagen fibers and ground substances
two types of fibroblasts
active
quiescent
active fibroblasts
abundant cytoplasm
pale nucleus
tissue construction
quiescent fibroblasts
resting state, less active
spindle shaped
adipocytes
specialized for storage of neutral fats/production of heat
widespread; signet ring appearance; thin rim of cytoplasm surrounding large lipid droplet, flattened nucleus
reticular cells
in reticular CT
synthesize reticular fibers type III
contribute to stroma of bone marrow and lymphoid tissues
free cells
macrophages
mast cells
plasma cells
macrophages
derive3d from monocytes produced in bone marrow
part o mononuclear phagocytic system
types of macrophages
monocytes kupffer cells alveolar macrophages Langerhans cells microglial cells tissue macrophages
macrophage function
defense, repair, immune, antigen presenting
mast cells
resp/GI tracts, deep layers os skin; release histamine
plasma cells
B lymphocytes derived
antibody producing cells
embryonic loose CT
mesenchyme: undifferentiated; pluripotent; ECM lacks fibers
mucoid: Wharton’s jelly; ECM high in hyaluronic acid, fibroblasts, type I collagen
areolar CT
most abundant; highly vascularized
packing tissue; fibroblasts, macrophages
flexible, not stress resistent
found adjacent to ET
reticular CT
bone marrow, lymphoid organs
type III collagen
creates trabecular network of cell-sheathed fibers
abundant macrophages
adipose CT
large aggregates of adipocytes
15-20% males; 20-25% females
adipose CT functions
energy storage
shock absorption (palms, soles)
thermal insulation
packing tissue holds organs in place
adipose CT types
unilocular
multilocular
unilocular
white fat
cells contain single large lipid droplet
most abundant in adult
multilocular
brown fat
cells contain numerous lipid droplets
abundant in newborns
dense irregular CT
fibroblasts and type I collagen
bundles of irregular collagen fibers
less flexible than loose CT, more stress resistant
found in dermis of skin, organ capsules, periosteum, perichondrium
dense regular CT
fibroblasts and type I collagen
bundles of parallel fibers
high tensile strength in one direction
tendons and ligaments
dense elastic CT
parallel bundles of elastic fibers
some type I and fibroblasts
dense elastic CT locations
ligamentum nuchae ligamentum flavum suspensory ligament of penis vocal ligament walls of elastic arteries