Unit 1 - DNA and the Genome - Structure of DNA Flashcards
Nucleic Acids
Nucleic acids are a group of molecules made of the same basic sub unit - the nucleotide.
Nucleotide composition
Base (usually shown as rectangle)
Sugar (usually shown as a pentagon)
Phosphate (usually shown as a circle)
Genetic information
Genetic information is stored via the base sequence. This sequence determines the shape and functions of proteins produced in the ribosome.
DeoxyriboNucleic Acid composition
Two chains of nucleotides, twisting in the infamous double helix shape. Held together by the hydrogen bonds between bases (weak), and the sugar-phosphate backbone (strong)
Prime ends of sugar
Sugar bonds with its own phosphate on 5’ end and to another phosphate on 3’ end.
(5’ end is on 4th corner of pentagon, don’t get confused)
Sugar- phosphate backbone
Strong chemical bond between phosphate of one nucleotide and the 3’ carbon in the sugar of another nucleotide joins nucleotides together to form a chain or strand.
Polynucleotides
Long chains of nucleotides.
Bases
4 different pairs - Adenosine (A-T) Thymine (T-A) Cytosine (C-G) Guanine (G-C) Bases are described as being complementary to one another (match up)
DNA base pair rules and bonds
Joined by weak hydrogen bonds between complementary base pairs.
Adenine always joins to Thymine
Cytosine always pairs with Guanine
Antiparallel Strands
When hydrogen bonds form between bases of polynucleotide strands, the strands run in opposite directions. (One strand from 5’ to 3’ and the other from 3’ to 5’)